Perez Maritza I
Columbia University, St. Luke's-Roosevelt Hospital Center, Beth Israel Medical Center, New York, New York, USA.
Cutis. 2005 Apr;75(4):217-22.
Melasma is a symmetric progressive hyperpigmentation of facial skin that occurs in all races but has a predilection for darker skin phenotypes. Melasma has been associated with hormonal imbalances, sun damage, and genetic predisposition. Clinically, melasma can be divided into centrofacial, malar, and mandibular according to the pigment distribution on the skin. On Wood light examination, the pigment can be found within the epidermis, where it will enhance, or within the dermis, where it will not enhance. Melasma can be classified as mild, moderate, or severe for evaluation and treatment purposes. In this article, we will discuss the objective evaluation of the patient with melasma, as well as the treatments based on disease severity. Further recommendations for maintenance in these patients also will be addressed.
黄褐斑是一种面部皮肤的对称性进行性色素沉着,所有种族均可发生,但更易见于肤色较深的人群。黄褐斑与激素失衡、阳光损伤和遗传易感性有关。临床上,黄褐斑可根据皮肤色素分布分为中央型、颧部型和下颌型。在伍德灯下检查,色素可在表皮内(此处会增强)或真皮内(此处不会增强)发现。为了评估和治疗目的,黄褐斑可分为轻度、中度或重度。在本文中,我们将讨论黄褐斑患者的客观评估以及基于疾病严重程度的治疗方法。还将讨论对这些患者维持治疗的进一步建议。