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下颌部黄褐斑

Mandibular melasma.

作者信息

Mandry Pagán R, Sánchez J L

机构信息

Department of Dermatology, University of Puerto Rico School of Medicine, San Juan 00936-5067.

出版信息

P R Health Sci J. 2000 Sep;19(3):231-4.

Abstract

Melasma is an acquired symmetrical brown hypermelanosis of the face. Three clinical patterns are recognized, namely centrofacial, malar and mandibular. This study addresses the clinical and histopathological features of ten women with mandibular melasma to determine its relation to other types of melasma. The mean age of the patients was 52 years and the onset of the disease occurred at an average age of 44 years. Sunlight aggravated the pigmentation in all cases. Only one patient was receiving hormonal therapy. Histopathologically, all patients demonstrated severe sundamage and hyperpigmentation of the epidermis. Nine of them had melanophages or melanin in the papillary dermis. We conclude than mandibular melasma may be a clinicopathologic entity different to other types of melasma.

摘要

黄褐斑是一种后天性的面部对称性棕色色素沉着过度。临床上可识别出三种类型,即面部中央型、颧部型和下颌型。本研究探讨了10名下颌型黄褐斑女性患者的临床和组织病理学特征,以确定其与其他类型黄褐斑的关系。患者的平均年龄为52岁,疾病发病的平均年龄为44岁。在所有病例中,阳光都会加重色素沉着。只有一名患者正在接受激素治疗。组织病理学上,所有患者均表现出严重的日光损伤和表皮色素沉着过度。其中9例在乳头层真皮中有噬黑素细胞或黑色素。我们得出结论,下颌型黄褐斑可能是一种与其他类型黄褐斑不同的临床病理实体。

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