Landi Francesco, Onder Graziano, Carpenter Iain, Garms-Homolova Vjenka, Bernabei Roberto
Department of Gerontology-Geriatric, Catholic University Sacred Heart, Rome, Italy.
Vaccine. 2005 Jun 10;23(30):3896-901. doi: 10.1016/j.vaccine.2005.03.008. Epub 2005 Apr 2.
The annual winter outbreak of influenza is one of the major cause of morbidity and mortality among frail elderly people. The aim of the present study was to identify prevalence and predictors of influenza vaccination in a large European population of frail and old people living in community. This was an observational study conducted in 11 European countries. We enrolled 3878 people 65 years and older already receiving home care services within the urban areas. All participants were assessed with the Minimum Data Set-Home Care (MDS-HC) instrument containing over 300 items, including socio-demographic, physical and cognitive characteristics of patients as well as medical diagnoses and medications received. A single question about the influenza vaccination status was used. The rate of influenza vaccination was around 59% of the studied sample. Significant geographical variations were evident in the prevalence of vaccination ranging from 31% of Prague (Czech Republic) to 88% of Rotterdam (The Netherlands). Overall, persons living alone were less likely to receive influenza vaccine as compared with those living with an informal caregiver (OR, 0.78; 95% CI 0.67-0.90). Similarly, cognitive impairment and presence of economic problems were associated with a lower likelihood of being vaccinated (OR: 0.69, 95% CI 0.59-0.80 and OR, 0.58; 95% CI 0.45-0.74, respectively). On the other hand, old age and comorbidity were associated with an higher probability of being vaccinated. In conclusion, more than 40% of subjects in this sample of home care patients in Europe did not receive influenza vaccination. Recommendations for influenza vaccination have not been adequately implemented.
每年冬季流感爆发是体弱老年人发病和死亡的主要原因之一。本研究的目的是确定欧洲大量居住在社区的体弱老年人中流感疫苗接种的普及率和预测因素。这是一项在11个欧洲国家进行的观察性研究。我们纳入了3878名65岁及以上且已在城市地区接受居家护理服务的人群。所有参与者均使用包含300多个项目的最低数据集 - 居家护理(MDS - HC)工具进行评估,这些项目包括患者的社会人口统计学、身体和认知特征以及医疗诊断和所接受的药物治疗。使用了一个关于流感疫苗接种状况的单一问题。流感疫苗接种率约为所研究样本的59%。疫苗接种普及率存在明显的地理差异,从捷克共和国布拉格的31%到荷兰鹿特丹的88%不等。总体而言,与有非正式照料者同住的人相比,独居者接种流感疫苗的可能性较小(比值比,0.78;95%置信区间0.67 - 0.90)。同样,认知障碍和存在经济问题与接种疫苗的可能性较低相关(比值比分别为:0.69,95%置信区间0.59 - 0.80;以及比值比,0.58;95%置信区间0.45 - 0.74)。另一方面,高龄和患有多种疾病与接种疫苗的可能性较高相关。总之,在欧洲这个居家护理患者样本中,超过40%的受试者未接种流感疫苗。流感疫苗接种的建议尚未得到充分落实。