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五个欧洲国家的流感疫苗接种覆盖率——基于人群的连续两个流感季节横断面分析

Influenza vaccination coverage rates in five European countries-a population-based cross-sectional analysis of two consecutive influenza seasons.

作者信息

Szucs Thomas D, Müller Daniela

机构信息

Institute for Social- and Preventive Medicine, University of Zurich, Department of Medical Economics, Gloriastrasse 18a, CH-8006 Zurich, Switzerland.

出版信息

Vaccine. 2005 Oct 17;23(43):5055-63. doi: 10.1016/j.vaccine.2005.06.005.

Abstract

INTRODUCTION

Influenza continues to be a considerable health problem in Europe. Vaccination is the only preventive measure, reducing mortality and morbidity of influenza in all age groups.

OBJECTIVES

The objective of this survey was to assess the level of influenza vaccination coverage during two consecutive influenza seasons (2002/2003 and 2003/2004) in six European countries, to understand the driving forces and barriers to vaccination and to determine vaccination intentions for the following winter.

METHODS

We conducted a random-sampling, telephone-based household survey among non-institutionalised individuals representative of the population aged 14 and over. The surveys used the same questionnaire for two consecutive winters: 2002/2003 and 2003/2004 data were used for Germany, Italy, Spain and the United Kingdom. 2001/2002 and 2002/2003 data were used for France. The data were subsequently pooled. Four target groups were determined for analysis: (1) persons aged 65 and over; (2) people working in the medical field; (3) persons suffering from chronic illness and (4) a group composed of persons aged 65 and over or working in the medical field or suffering from a chronic illness.

RESULTS

The overall sample consisted of 20,118 individuals. The influenza vaccination coverage rate increased from 21.3% in the first season to 23.2% in the second season. The increase in coverage is statistically significant (p=0.01). The most frequent reasons for being vaccinated given by vaccines were: influenza, considered to be a serious illness which people wanted to avoid (55.8%), having received advice from the family doctor or nurse to be vaccinated (55.2%) and not wanting to infect family and friends (36.1%). Reasons for not being vaccinated mentioned by people who have never been vaccinated were: not expecting to catch influenza (40.4%), not having considered vaccination before (33.3%) and not having received a recommendation from the family doctor to be vaccinated (27.3%). Options encouraging influenza vaccination are: recommendation by the family doctor or nurse (53.1%), more available information on the vaccine regarding efficacy and tolerance (32.1%) and more information available about the disease (26.7%). Adjusted odds ratios for target group vaccination were between 3.6 (Germany) and 13.7 (UK). Vaccination rates among healthcare workers were generally very low. Adjusted odds ratios were between 0.7 (Germany) and 1.5 (Spain).

CONCLUSION

The vaccination coverage during the second season increased in comparison to the first season. The family doctor is the most important source of encouragement for people to be vaccinated against influenza. It seems that the public would be more likely to be vaccinated if they had more information on the efficacy and tolerance of the vaccine, as well as the disease. We, therefore, suggest that family doctors be better informed on influenza vaccine and the disease itself, so that they can actively inform their patients on these topics.

摘要

引言

在欧洲,流感仍然是一个严重的健康问题。接种疫苗是唯一的预防措施,可降低所有年龄组流感的死亡率和发病率。

目的

本次调查的目的是评估六个欧洲国家在连续两个流感季节(2002/2003年和2003/2004年)的流感疫苗接种覆盖率,了解接种疫苗的驱动力和障碍,并确定下一个冬季的接种意向。

方法

我们对14岁及以上具有代表性的非机构化个人进行了随机抽样的电话家庭调查。连续两个冬季的调查使用相同的问卷:德国、意大利、西班牙和英国使用2002/2003年和2003/2004年的数据。法国使用2001/2002年和2002/2003年的数据。随后将数据汇总。确定了四个目标群体进行分析:(1)65岁及以上的人群;(2)从事医疗领域工作的人员;(3)患有慢性病的人员;(4)由65岁及以上、从事医疗领域工作或患有慢性病的人员组成的群体。

结果

总样本包括20118人。流感疫苗接种覆盖率从第一季的21.3%升至第二季的23.2%。覆盖率的增加具有统计学意义(p=0.01)。接种疫苗者给出的最常见接种原因是:认为流感是一种人们想要避免的严重疾病(55.8%),接受了家庭医生或护士的接种建议(55.2%),以及不想感染家人和朋友(36.1%)。从未接种过疫苗的人提到的未接种原因是:不认为自己会感染流感(40.4%),之前没有考虑过接种(33.3%),以及没有得到家庭医生的接种建议(27.3%)。鼓励接种流感疫苗的因素有:家庭医生或护士的建议(53.1%),关于疫苗效力和耐受性的更多可用信息(32.1%),以及关于该疾病的更多可用信息(26.7%)。目标群体接种的调整优势比在3.6(德国)至13.7(英国)之间。医护人员的接种率普遍很低。调整优势比在0.7(德国)至1.5(西班牙)之间。

结论

与第一季相比,第二季的疫苗接种覆盖率有所提高。家庭医生是鼓励人们接种流感疫苗的最重要来源。如果公众能获得更多关于疫苗效力和耐受性以及该疾病的信息,他们似乎更有可能接种疫苗。因此,我们建议家庭医生更好地了解流感疫苗和疾病本身,以便他们能够积极向患者宣传这些话题。

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