19q13在滤泡性甲状腺腺瘤中的作用。
Involvement of 19q13 in follicular thyroid adenoma.
作者信息
Dal Cin P, Sneyers W, Aly M S, Segers A, Ostijn F, Van Damme B, Van Den Berghe H
机构信息
Centre for Human Genetics, University of Leuven, Belgium.
出版信息
Cancer Genet Cytogenet. 1992 May;60(1):99-101. doi: 10.1016/0165-4608(92)90244-3.
PMID:1591716
Abstract
Cytogenetic investigation of a follicular thyroid adenoma from a 31-year-old woman showed a t(16;19)(q12;q13), as the sole chromosome abnormality. As five more cases with 19q13 involvement have been described, we suggest that the terminal region of the long arm of chromosome 19 is important for the development of follicular thyroid adenoma.
摘要
对一名31岁女性的滤泡性甲状腺腺瘤进行的细胞遗传学研究显示，t(16;19)(q12;q13)是唯一的染色体异常。由于已经描述了另外5例涉及19q13的病例，我们认为19号染色体长臂的末端区域对滤泡性甲状腺腺瘤的发生发展很重要。
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