Alyaseen Samer A, Piper Kerryl E, Rouse Mark S, Steckelberg James M, Patel Robin
Division of Infectious Diseases, Department of Medicine, Mayo Clinic College of Medicine, 200 First St. SW, Rochester, MN 55905, USA.
Antimicrob Agents Chemother. 2005 Jun;49(6):2543-5. doi: 10.1128/AAC.49.6.2543-2545.2005.
Exposure of ciprofloxacin- and cefepime-susceptible Pseudomonas aeruginosa isolates to increasing concentrations of ciprofloxacin selected for ciprofloxacin resistance in 26/27 and cefepime nonsusceptibility in 7/27 isolates. Exposure of the isolates to increasing concentrations of cefepime selected for cefepime nonsusceptibility in 20/27 isolates but not for ciprofloxacin resistance.
将对环丙沙星和头孢吡肟敏感的铜绿假单胞菌分离株暴露于浓度不断增加的环丙沙星中,在27株中有26株产生了环丙沙星耐药性,在27株中有7株产生了头孢吡肟不敏感性。将这些分离株暴露于浓度不断增加的头孢吡肟中,在27株中有20株产生了头孢吡肟不敏感性,但未产生环丙沙星耐药性。