Dayer E
Consilia Laboratoires et conseils médicaux SA, 1950 Sion
Rev Med Suisse. 2005 Apr 13;1(15):1004-6, 1008-9.
The clinical setting defines the use of different methodology to detect allergen-specific IgE antibodies. In primary care, near the patient detection methods are useful as alternative to skin tests. The use of quantitative screening methods for atopy (Phadiatop) has been shown to improve the allergy diagnosis by the practicionner Such methods are very useful for their negative predictive value. Moreover, the dissociation between seasonal and perennial allergy is easier. For the use of specialist, quantitative results of allergen-specific IgE can be related to the probability of a clinical reaction to a given allergen. Clinical decision points have been established for common food allergens associated with atopic eczema in children.
临床环境决定了使用不同方法来检测过敏原特异性IgE抗体。在初级保健中,床边检测方法作为皮肤试验的替代方法很有用。已证明使用特应性定量筛查方法(Phadiatop)可改善从业者的过敏诊断。这些方法因其阴性预测价值而非常有用。此外,季节性和常年性过敏之间的区分更容易。对于专科医生而言,过敏原特异性IgE的定量结果可与对特定过敏原发生临床反应的概率相关。已经为与儿童特应性皮炎相关的常见食物过敏原建立了临床决策点。