Hochreutener H
Dermatologische Universitäts-Poliklinik Zürich, Ostschweizerisches Kinderspital St. Gallen.
Monatsschr Kinderheilkd. 1991 Sep;139(9):618-25.
Forty children with atopic dermatitis were evaluated for history, clinical features and allergologic-immunologic parameters. Lichenoid skin lesions were found in 67.5%, follicular lesions in 57.5%, and eczematoid lesions in 50% in children. 25% of children suffered from associated food allergy, 15% from respiratory atopy, and 5% from contact urticaria. The diagnostic efficiency to show specific sensitization was 93% for Pediatric Phadiatop, 90% for Food-Multidisc (fx5 Pharmacia), 88% for skin tests (Prick), 73% for elevated total serum IgE, 65% for Phadiatop, and 60% for family history. The classification of atopic dermatitis into an extrinsic type with specific sensitizations to allergens and into an intrinsic type without specific sensitizations appears to be useful because specific sensitizations significantly correlate with severer skin condition and disease course.
对40名特应性皮炎患儿进行了病史、临床特征及变应性免疫参数评估。患儿中，67.5%有苔藓样皮肤损害，57.5%有毛囊性损害，50%有湿疹样损害。25%的患儿伴有食物过敏，15%有呼吸道特应性，5%有接触性荨麻疹。小儿变应原筛查试验（Pediatric Phadiatop）显示特异性致敏的诊断效率为93%，食物多盘试验（Food-Multidisc，fx5 Pharmacia）为90%，皮肤点刺试验为88%，血清总IgE升高为73%，变应原筛查试验（Phadiatop）为65%，家族史为60%。将特应性皮炎分为对变应原具有特异性致敏的外源性类型和无特异性致敏的内源性类型似乎是有用的，因为特异性致敏与更严重的皮肤状况和病程显著相关。
