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[自然分娩及剖宫产(伴或不伴分娩期子宫扭转)过程中奶牛急性期蛋白触珠蛋白的变化]

[The change of acute phase protein haptoglobin in cattle during spontaneous labor and Caesarean section with or without torsio uteri intrapartum].

作者信息

Schönfelder Axel, Schrödl Wieland, Krüger Monika, Richter Andreas, Sobiraj Axel

机构信息

Ambulatorische und Geburtshilfliche Tierklinik, Veterinärmedizinische Fakultät, Universität Leipzig.

出版信息

Berl Munch Tierarztl Wochenschr. 2005 May-Jun;118(5-6):240-6.

Abstract

The change of haptoglobin concentration in cattle with dystocia after torsio uteri which lead to Caesarean section is regarded in contrast to haptoglobin concentrations in cattle at parturitions with undisturbed puerperium and Caesarean section without torsio uteri intra partum. Animals with natural parturition had low haptoglobin concentrations with slight changes, for a slightly increased haptoglobin concentration was seen as physiologic. Also surgical treatment such as Caesarean section did not result in changes of haptoglobin concentration. Thus, the curve of animal patients with anomalies concerning position or with a too large fetus (relatively or absolutly) was nearly identical to the curve of animals with regular parturitions over the first four days after surgery. Not before the fifth day after surgery, a moderate increase of haptoglobin could be observed. Animals with dystocia after torsio uteri intra partum showed significantly higher haptoglobin concentrations in contrast to controls over the time of investigation. The correlation of haptoglobin concentrations in animal patients with torsio uteri bin concentration shortly after surgery an additionally significant increase of haptoglobin concentration could be observed in later fertile cattles but not in later infertile cattle with torsio uteri. In two cows with torsio uteri and ovariohysterectomy haptoglobin concentrations decreased rapidly. Haptoglobin concentration may serve as an indicator for the degree of impairment of the uterus during a parturition as well as a predictor for regenerative potential.

摘要

与未受干扰的产褥期分娩及产时无子宫扭转的剖宫产牛的触珠蛋白浓度相比,产时子宫扭转后导致剖宫产的难产牛的触珠蛋白浓度变化受到关注。自然分娩的动物触珠蛋白浓度较低且变化轻微,因为触珠蛋白浓度稍有增加被视为生理现象。同样,剖宫产等外科治疗也未导致触珠蛋白浓度变化。因此,在手术后的头四天,胎位异常或胎儿过大(相对或绝对)的动物患者曲线与正常分娩动物的曲线几乎相同。直到手术后第五天,才观察到触珠蛋白有适度增加。与对照组相比,产时子宫扭转后难产的动物在整个研究期间触珠蛋白浓度显著更高。子宫扭转动物患者触珠蛋白浓度与对照组的相关性在手术后不久触珠蛋白浓度有额外显著增加,在后来可育的牛中可以观察到,但在后来不育的子宫扭转牛中则没有。在两头进行子宫扭转和卵巢子宫切除术的奶牛中,触珠蛋白浓度迅速下降。触珠蛋白浓度可作为分娩期间子宫受损程度的指标以及再生潜力的预测指标。

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