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镰状细胞病围手术期输血并发迟发性溶血性输血反应和高溶血现象

Delayed haemolytic transfusion reaction and hyperhaemolysis complicating peri-operative blood transfusion in sickle cell disease.

作者信息

McGlennan A P, Grundy E M

机构信息

Whittington Hospital, Highgate Hill, Archway, London N19 5NF, UK.

出版信息

Anaesthesia. 2005 Jun;60(6):609-12. doi: 10.1111/j.1365-2044.2005.04188.x.

DOI:10.1111/j.1365-2044.2005.04188.x
PMID:15918834
Abstract

We present a case of delayed haemolytic transfusion reaction and hyperhaemolysis syndrome in a patient with sickle cell disease. A 32-year-old woman with a history of sickle cell disease was scheduled for total hip replacement. She was transfused pre-operatively and suffered a delayed haemolytic transfusion reaction. Postoperatively the patient continued to haemolyse, despite the use of antigen compatible blood, suggesting that she had developed hyperhaemolysis syndrome following her delayed haemolytic transfusion reaction. Although rare, both conditions must be borne in mind when dealing with patients who have undergone multiple transfusions.

摘要

我们报告了一例镰状细胞病患者发生迟发性溶血性输血反应和高溶血综合征的病例。一名有镰状细胞病病史的32岁女性计划进行全髋关节置换术。她在术前接受了输血,并发生了迟发性溶血性输血反应。术后,尽管使用了抗原相容的血液,患者仍继续溶血,这表明她在迟发性溶血性输血反应后发生了高溶血综合征。尽管这两种情况都很罕见,但在处理接受过多次输血的患者时必须牢记。

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Delayed haemolytic transfusion reaction and hyperhaemolysis complicating peri-operative blood transfusion in sickle cell disease.镰状细胞病围手术期输血并发迟发性溶血性输血反应和高溶血现象
Anaesthesia. 2005 Jun;60(6):609-12. doi: 10.1111/j.1365-2044.2005.04188.x.
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