抗磷脂（休斯）综合征的种族和地理差异。
Ethnic and geographical variation in antiphospholipid (Hughes) syndrome.
作者信息
Uthman I, Khamashta M
机构信息
American University of Beirut, Medical Centre, PO Box 113-6044, Beirut, Lebanon.
出版信息
Ann Rheum Dis. 2005 Dec;64(12):1671-6. doi: 10.1136/ard.2005.038448. Epub 2005 May 26.
Abstract
Investigation of the clinical epidemiology of the antiphospholipid syndrome (APS) is in its early stages. During the past 20 years, studies of antiphospholipid antibodies (aPL) and APS have been made in many countries and ethno-geographical groups. aPL appear to occur in all populations studied, with some variations noted in their frequency and in the clinical complications. Environmental and genetic factors contribute to ethnic variation and susceptibility to APS and thus inter-ethnic differences in disease patterns may be due to environmental or genetic factors, or both.
摘要
抗磷脂综合征（APS）的临床流行病学研究尚处于早期阶段。在过去20年里，许多国家和不同种族地理群体都开展了抗磷脂抗体（aPL）和APS的研究。在所有研究的人群中似乎都存在aPL，但其频率和临床并发症存在一些差异。环境和遗传因素导致了种族差异以及对APS的易感性，因此疾病模式的种族间差异可能是由环境因素或遗传因素，或两者共同作用所致。
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