Bertrais Sandrine, Beyeme-Ondoua Jean-Paul, Czernichow Sébastien, Galan Pilar, Hercberg Serge, Oppert Jean-Michel
UMR INSERM U557/INRA U1125/CNAM EA 3200-MR, 5 rue du Vertbois, F-75003 Paris, France.
Obes Res. 2005 May;13(5):936-44. doi: 10.1038/oby.2005.108.
To study the relationships of time spent in sedentary occupations with the National Cholesterol Education Program-defined metabolic syndrome (MS), taking into account the habitual level of physical activity (PA).
This was a cross-sectional analysis in 1902 men and 1932 women 50 to 69 years of age participating in the French Supplementation with Antioxidant Vitamins and Minerals study. We assessed past-year PA, television watching or computer use, and reading during leisure with the Modifiable Activity Questionnaire. Subjects who performed at least 150 min/wk of moderate-intensity PA (3 to 6 metabolic equivalent tasks) or 60 min/wk of vigorous PA (>6 metabolic equivalent tasks) were considered as meeting recommended levels.
The frequency of most MS components increased with time spent in front of a screen and decreased with increasing PA levels. The likelihood to have MS, adjusted for age, education, and smoking, was decreased by one-third in subjects meeting moderate PA guidelines and by two-thirds in subjects meeting vigorous PA recommendations [odds ratio (95% CI), 0.34 (0.17 to 0.66) in women, 0.44 (0.28 to 0.68) in men] compared with those with insufficient PA. Independently of PA levels, time spent in front of a screen was positively associated with the likelihood to have the MS in women [odds ratio (95% CI), 3.30 (2.04 to 5.34)], whereas in both sexes, no association was found with time spent reading.
The relationship of the MS with a sedentary lifestyle differs according to sex and type of sedentary occupation. These results suggest the need to assess selected indicators of sedentary behavior in preventive programs.
考虑到习惯性身体活动（PA）水平，研究从事久坐职业的时间与国家胆固醇教育计划定义的代谢综合征（MS）之间的关系。
这是一项对1902名50至69岁男性和1932名50至69岁女性进行的横断面分析，这些人参与了法国抗氧化维生素和矿物质补充研究。我们使用可改变活动问卷评估了过去一年的PA、看电视或使用电脑以及休闲时阅读的情况。每周进行至少150分钟中等强度PA（3至6代谢当量任务）或60分钟剧烈PA（>6代谢当量任务）的受试者被视为达到推荐水平。
大多数MS组分的频率随着在屏幕前花费的时间增加而增加，随着PA水平的提高而降低。在根据年龄、教育程度和吸烟情况进行调整后，达到中等PA指南的受试者患MS的可能性降低了三分之一，达到剧烈PA建议的受试者患MS的可能性降低了三分之二[女性的优势比（95%可信区间）为0.34（0.17至0.66），男性为0.44（0.28至0.68）]，与PA不足的受试者相比。独立于PA水平，女性在屏幕前花费的时间与患MS的可能性呈正相关[优势比（95%可信区间）为3.30（2.04至5.34）]，而在两性中，未发现与阅读时间存在关联。
MS与久坐生活方式的关系因性别和久坐职业类型而异。这些结果表明在预防计划中需要评估久坐行为的选定指标。
