Zipfel Cyril, Felix Georg
Botanical Institute, Zurich-Basel Plant Science Centre, University of Basel, CH-4056 Basel, Switzerland.
Curr Opin Plant Biol. 2005 Aug;8(4):353-60. doi: 10.1016/j.pbi.2005.05.004.
Plants and animals can recognize potential pathogens by detecting pathogen-associated molecular patterns (PAMPs). Significant advances over the past few years have begun to unveil the molecular basis of PAMP perception by pattern recognition receptors (PRRs). Although these discoveries highlight common recognition strategies among higher eukaryotes, they also show differences with respect to the nature of the receptors involved and the exact molecular patterns recognized. This suggests a convergent evolution of microbe sensing by the innate immune systems of these various organisms.
植物和动物可以通过检测病原体相关分子模式（PAMPs）来识别潜在的病原体。在过去几年中取得的重大进展已开始揭示模式识别受体（PRRs）识别PAMPs的分子基础。尽管这些发现凸显了高等真核生物之间常见的识别策略，但它们在涉及的受体性质和所识别的确切分子模式方面也存在差异。这表明这些不同生物体的先天免疫系统对微生物的感知存在趋同进化。
