宿主-微生物相互作用：塑造植物免疫反应的进化

Host-microbe interactions: shaping the evolution of the plant immune response.

作者信息

Chisholm Stephen T, Coaker Gitta, Day Brad, Staskawicz Brian J

机构信息

Department of Plant and Microbial Biology, 111 Koshland Hall, University of California, Berkeley, Berkeley, CA 94720, USA.

出版信息

Cell. 2006 Feb 24;124(4):803-14. doi: 10.1016/j.cell.2006.02.008.

DOI:10.1016/j.cell.2006.02.008

PMID:16497589

Abstract

The evolution of the plant immune response has culminated in a highly effective defense system that is able to resist potential attack by microbial pathogens. The primary immune response is referred to as PAMP-triggered immunity (PTI) and has evolved to recognize common features of microbial pathogens. In the coevolution of host-microbe interactions, pathogens acquired the ability to deliver effector proteins to the plant cell to suppress PTI, allowing pathogen growth and disease. In response to the delivery of pathogen effector proteins, plants acquired surveillance proteins (R proteins) to either directly or indirectly monitor the presence of the pathogen effector proteins. In this review, taking an evolutionary perspective, we highlight important discoveries over the last decade about the plant immune response.

摘要

植物免疫反应的进化最终形成了一种高效的防御系统，能够抵御微生物病原体的潜在攻击。主要的免疫反应被称为病原体相关分子模式触发的免疫（PTI），并且已经进化到能够识别微生物病原体的共同特征。在宿主 - 微生物相互作用的共同进化过程中，病原体获得了将效应蛋白传递到植物细胞以抑制PTI的能力，从而使病原体得以生长并引发疾病。作为对病原体效应蛋白传递的响应，植物获得了监测蛋白（R蛋白），以直接或间接监测病原体效应蛋白的存在。在本综述中，我们从进化的角度突出了过去十年中关于植物免疫反应的重要发现。