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青春期后兔子脾、肾及肠系膜动静脉血中血细胞计数的比较。

Comparison of blood counts in splenic, renal and mesenteric arterial and venous blood in post-pubertal rabbits.

作者信息

Yang Z-W, Li J-A, Yang M-H, Feng Y-S, Tang Z, Dai X-S, Wang H-Y, Yin Q-Q, Gao Y, Li J, He X-L, Zhang Y, An Q

机构信息

Morphometric Research Laboratory, North Sichuan Medical College, 234 Fujiang Road, Nanchong, Sichuan Province 637007, China.

出版信息

Res Vet Sci. 2005 Oct;79(2):149-54. doi: 10.1016/j.rvsc.2004.11.008. Epub 2005 Jan 21.

DOI:10.1016/j.rvsc.2004.11.008
PMID:15924932
Abstract

OBJECTIVES

To compare blood counts between arterial and venous blood to and from visceral organs and indirectly look into the function of the organs.

METHODS

Splenic, renal and superior mesenteric arterial and venous blood samples were obtained from the arteries and veins in 38 post-pubertal rabbits and blood profile, including complete and differential blood counts, haemoglobin concentration and haematocrit, were measured with an automatic haematology analyser.

RESULTS AND CONCLUSIONS

The rabbit spleen released a large amount of leucocytes (both lymphocytes and granulocytes) into the splenic venous blood (a venous increase of 33% in total leucocyte count), and also received more leucocytes (36-58% more in terms of concentration) from the artery than the kidney or intestine. Significantly fewer red blood cells were present in the renal venous blood than in the arterial blood (a venous reduction of 5% in erythrocyte count), but it remains to be clarified why and how the reduction was induced. More than 3-4% of water might be taken into the mesenteric venous blood during microcirculation (a venous reduction of 3-4% in erythrocyte-related parameters) and a significant number of leucocytes (mainly large leucocytes) in the mesenteric blood capillaries might migrate into the surrounding intestinal tissue (a venous reduction of 13% in leucocyte count).

摘要

目的

比较进出内脏器官的动脉血和静脉血的血细胞计数,并间接探究器官的功能。

方法

从38只青春期后的兔子的动脉和静脉获取脾、肾及肠系膜上动脉和静脉血样本,使用自动血液分析仪测量血液指标,包括全血细胞计数和分类计数、血红蛋白浓度及血细胞比容。

结果与结论

兔脾脏向脾静脉血中释放大量白细胞(淋巴细胞和粒细胞)(白细胞总数静脉血增加33%),且从动脉接收的白细胞比肾脏或肠道更多(浓度方面多36% - 58%)。肾静脉血中的红细胞明显少于动脉血(红细胞计数静脉血减少5%),但减少的原因及机制仍有待阐明。微循环过程中,超过3% - 4%的水分可能进入肠系膜静脉血(与红细胞相关参数静脉血减少3% - 4%),肠系膜毛细血管中的大量白细胞(主要是大白细胞)可能迁移至周围肠组织(白细胞计数静脉血减少13%)。

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