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家兔特定血液学参数的年龄相关变化。

Age-related changes in selected haematology parameters in rabbits.

作者信息

Jeklova E, Leva L, Knotigova P, Faldyna M

机构信息

Department of Immunology, Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic.

出版信息

Res Vet Sci. 2009 Jun;86(3):525-8. doi: 10.1016/j.rvsc.2008.10.007. Epub 2008 Nov 28.

Abstract

Even though there is an abundance of information on the reference values of haematological parameters in adult rabbits, a little is known about the changes in haematology in newborn rabbits or during their postnatal development. Therefore, the aim of our study was to investigate changes in red blood cells (RBC), white blood cells (WBC) and differential leukocyte counts in SPF New Zealand White rabbits from the age of one day to 20 weeks. Significant age-related changes during the first four weeks of life were detected. These included an increase of RBC and WBC, reversal of the neutrophil/lymphocyte ratio and increase of total counts of eosinophils and basophils. From the age of six weeks of life, all of the studied haematological parameters were comparable to those of adult rabbits.

摘要

尽管有大量关于成年兔血液学参数参考值的信息,但对于新生兔或其出生后发育过程中的血液学变化却知之甚少。因此,我们研究的目的是调查无特定病原体(SPF)的新西兰白兔从1日龄到20周龄期间红细胞(RBC)、白细胞(WBC)和白细胞分类计数的变化。在出生后的前四周检测到了与年龄相关的显著变化。这些变化包括红细胞和白细胞增加、中性粒细胞/淋巴细胞比例逆转以及嗜酸性粒细胞和嗜碱性粒细胞总数增加。从六周龄开始,所有研究的血液学参数都与成年兔相当。

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