Beamis John F
Department of Pulmonary and Critical Care Medicine, Lahey Clinic, Burlington, Massachusetts 01805, USA.
Curr Opin Pulm Med. 2005 Jul;11(4):292-5. doi: 10.1097/01.mcp.0000166593.87794.bd.
This paper reviews the recent literature on the management of malignant large airway obstruction using interventional pulmonology techniques.
A number of interventional techniques have been developed during the last 25 years. Recent papers expand on this work, reaffirming the utility of laser bronchoscopy; introducing newer, less expensive technologies with similar outcomes; and attesting to the benefit of airway stenting. Electrocautery is likely to replace laser as the preferred tool for coagulation of intrinsic airway tumors because it is readily available in most hospitals and is much less expensive to set up. Several large series have attested to the excellent results achieved with airway stents placed to relieve extrinsic large airway obstruction. Investigators are using new technologies in an attempt to predict the proper location of stent placement to achieve maximum palliation of symptoms. Published guidelines are available describing the application of interventional techniques.
A number of interventional pulmonology techniques are available to treat large airway obstruction from malignant tumor. Clinical studies and personal experience attest to their utility. More evidenced-based studies are needed to help determine the best technique for a particular type of obstruction.
本文综述了近期关于采用介入肺脏病学技术治疗恶性大气道阻塞的文献。
在过去25年中已开发出多种介入技术。近期的论文对这项工作进行了拓展,再次肯定了激光支气管镜检查的效用;介绍了具有相似效果但成本更低的更新技术;并证实了气道支架置入的益处。电灼术可能会取代激光,成为治疗气道内肿瘤凝固的首选工具,因为大多数医院都容易获得该设备,且设备安装成本要低得多。几个大型系列研究证实,置入气道支架以缓解外在性大气道阻塞可取得优异效果。研究人员正在使用新技术,试图预测支架置入的合适位置,以最大程度缓解症状。现有已发表的指南描述了介入技术的应用。
有多种介入肺脏病学技术可用于治疗恶性肿瘤所致的大气道阻塞。临床研究和个人经验证实了它们的效用。需要更多基于证据的研究,以帮助确定针对特定类型阻塞的最佳技术。