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介入肺病学:内科医师的最新进展。

Interventional pulmonology: an update for internal medicine physicians.

机构信息

Department of Medicine, University of Calgary Calgary, Alberta, Canada -

出版信息

Minerva Med. 2014 Jun;105(3):197-209.

Abstract

Interventional pulmonology is a subspecialty that uses advanced diagnostic and therapeutic procedures to care for patients with benign and malignant diseases of the lung, airways and pleura. There has been a rapid proliferation of new pulmonary procedural technologies over the last decade. Common diagnostic applications include endobronchial ultrasound, guided bronchoscopy and a number of pleural disease interventions. Endobronchial ultrasound is performed with a specially design flexible bronchoscope and allows safe and accurate sampling of intrathoracic structures through the airway wall under direct visualization. Guided bronchoscopy methods are granting significant improvement in the diagnostic yield of flexible bronchoscopy. Virtual bronchoscopy, radial probe endobronchial ultrasound and electromagnetic navigational bronchoscopy are examples of these methods. Interventional pulmonologists can also be trained to perform ultrasound guided thoracentesis, closed-needle pleural biopsy and medical thoracoscopy to help in the diagnosis of different pleural pathologies. Therapeutic applications can be used to efficiently bring symptomatic relief of benign and malignant central airway obstruction by using a myriad of flexible and rigid bronchoscopy techniques. Airway stenting and ablative techniques such as laser, electrocautery, cryosurgery and microdebrider techniques are example of resources that can be used by interventional pulmonologists for therapeutic purposes. A number of effective therapies for the management of malignant pleural disease have been studied in recent years, including chemical pleurodesis and tunnelled pleural catheters, greatly adding to our understanding of which therapy to use in which patient. In addition, flexible bronchoscopy approaches to more common disease, such as asthma and chronic obstructive pulmonary disease are currently available or are being developed. This update aims to provide the internal medicine physician with a brief overview of some of the common clinical procedures performed by interventional pulmonary specialists and the current indications and evidence for their use.

摘要

介入肺脏医学是一个亚专科,利用先进的诊断和治疗技术来治疗肺部、气道和胸膜的良恶性疾病。在过去十年中,新的肺脏介入技术迅速发展。常见的诊断应用包括支气管内超声、引导下支气管镜检查和许多胸膜疾病介入。支气管内超声是使用专门设计的柔性支气管镜进行的,通过气道壁在直接可视化下安全准确地对胸内结构进行采样。引导下支气管镜检查方法显著提高了柔性支气管镜的诊断效果。虚拟支气管镜检查、径向探头支气管内超声和电磁导航支气管镜检查就是这些方法的例子。介入肺科医生也可以接受培训,以进行超声引导下胸腔穿刺术、闭式针吸胸膜活检和内科胸腔镜检查,以帮助诊断不同的胸膜病变。治疗应用可用于通过使用各种柔性和刚性支气管镜技术,有效地缓解良性和恶性中央气道阻塞的症状。气道支架和消融技术,如激光、电烙术、冷冻手术和微动力清除术,都是介入肺科医生可用于治疗目的的资源示例。近年来,已经研究了许多治疗恶性胸膜疾病的有效疗法,包括化学胸膜固定术和经皮胸膜腔引流管,这极大地增加了我们对哪种疗法适用于哪种患者的理解。此外,针对更常见疾病(如哮喘和慢性阻塞性肺疾病)的柔性支气管镜检查方法目前已经可用或正在开发中。本更新旨在为内科医生提供介入性肺科专家进行的一些常见临床操作的简要概述,以及这些操作的当前适应证和证据。

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