Harrison G G, Bird A R, Jacobs P, Coghlan P, Byrne M J, Ozinsky J, Besseling J L
Department of Anaesthesia, University of Cape Town, South Africa.
J Clin Apher. 1992;7(1):12-7. doi: 10.1002/jca.2920070105.
Inadvertent hypothermia due to massive infusion of stored blood can be prevented by pretransfusion warming. One approach is the heating of individual packs by means of electromagnetic conduction, which is a method safely used over the last 25 years. The prototype instrument, which has now been re-engineered, can effectively raise the temperature of a unit of blood to approximately 33 degrees C in less than 3 minutes. Using this new model, we found, in vitro, a modest increase in free plasma haemoglobin, but this was not accompanied by any change in potassium or lactic dehydrogenase levels and the mean red cell fragility was unaltered. In vivo, the survival of autologous red cells that had been stored for 33 days and then infused as a concentrate, having a mean haematocrit of 0.60, was measured at 24 hours and 21 days. Each donor acted as his own control. In paired studies, pretransfusion radiofrequency heating was shown to have no deleterious effect when compared to measurements using the unwarmed blood pack. It is concluded that this method can be recommended as safe.
通过输血前加温可预防因大量输注库存血导致的意外体温过低。一种方法是利用电磁传导对单个血袋进行加热，这是过去25年一直安全使用的方法。现已重新设计的原型仪器能够在不到3分钟的时间内将一单位血液的温度有效提高到约33摄氏度。使用这种新模型，我们在体外发现游离血浆血红蛋白略有增加，但钾或乳酸脱氢酶水平没有任何变化，且平均红细胞脆性未改变。在体内，对储存33天然后作为浓缩液输注的自体红细胞进行了24小时和21天的存活率测量，其平均血细胞比容为0.60。每位供体都作为自己的对照。在配对研究中，与使用未加温血袋的测量结果相比，输血前射频加热未显示出有害影响。结论是该方法可被推荐为安全方法。
