Sancho E, Ferrando M D, Andreu E, Gamon M
Dept. Animal Physiology, Faculty of Biological Sciences, University of Valencia, Spain.
J Environ Sci Health B. 1992 Apr;27(2):209-21. doi: 10.1080/03601239209372775.
The toxicity, accumulation, and elimination of diazinon were investigated for the european eel, Anguilla anguilla. The 24, 48, 72 and 96-h median lethal concentrations (LC50) were 0.16, 0.11, 0.09 and 0.08 mg/L, respectively. Fish exposed to sublethal concentration (0.042 mg/L) accumulated diazinon in liver and muscle tissues. Bioconcentration factors (BCF) of diazinon were 1850 in liver, and 775 in muscle over the 96-h exposure period. Upon removal from diazinon containing water the contaminated fish rapidly eliminated diazinon. The excretion rate constants of this insecticide were 0.108 h-1 for liver and 0.016 h-1 for muscle. Diazinon half-lives were 16.6 and 33.2 hours for liver and muscle, respectively.
研究了欧洲鳗鲡（Anguilla anguilla）对二嗪农的毒性、蓄积和消除情况。24、48、72和96小时的半数致死浓度（LC50）分别为0.16、0.11、0.09和0.08毫克/升。暴露于亚致死浓度（0.042毫克/升）的鱼类在肝脏和肌肉组织中蓄积了二嗪农。在96小时的暴露期内，二嗪农在肝脏中的生物富集因子（BCF）为1850，在肌肉中的为775。从含二嗪农的水中捞出后，受污染的鱼类迅速排出二嗪农。这种杀虫剂在肝脏中的排泄速率常数为0.108小时-1，在肌肉中的为0.016小时-1。二嗪农在肝脏和肌肉中的半衰期分别为16.6小时和33.2小时。
