Connor M, Rheeder P, Bryer A, Meredith M, Beukes M, Dubb A, Fritz V
Division of Neurology, Department of Neurosciences, School of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa.
S Afr Med J. 2005 May;95(5):334-9.
Incidence of stroke is increasing in sub-Saharan Africa and stroke prevention is an essential component of successful stroke management. General practitioners (GPs) are well placed to manage stroke risk factors. To design appropriate strategies for risk factor reduction we need to know the risk factor prevalence in each of the population groups attending GPs. The aim of this study was to establish the prevalence of stroke risk factors in the South African general practice population.
We conducted a multicentre, observational study of patients attending general practice in South Africa. Two hundred general practices were randomly selected from lists provided by pharmaceutical representatives. Each GP approached 50 consecutive patients aged 30 years and older. Patients completed an information sheet and the GP documented the patient's risk factors. The resulting sample is relevant if not necessarily representative in a statistical sense.
A total of 9 731 questionnaires were returned out of a possible 10,000. The mean age of particpants was 50.7 years. Seventy-six per cent had 1 or more risk factors and 40% had 2 or more risk factors. Hypertension was the commonest risk factor in all population groups (55%) but was highest in black patients (59%). Dyslipidaemia was commonest in whites (37%) and least common in blacks (5%). Diabetes was commonest in Asians (24%) but least common in whites (8%). Risk factors other than smoking increased with age.
This study provides unique data on the prevalence of stroke risk factors in a South African general practice population. Risk factors are common in all population groups, but differ in distribution among the groups. There is considerable opportunity to reduce the burden of stroke in South Africa through GP screening for and treatment of risk factors.
撒哈拉以南非洲地区中风的发病率正在上升,中风预防是成功管理中风的重要组成部分。全科医生(GP)在管理中风风险因素方面具有优势。为了设计适当的降低风险因素的策略,我们需要了解在全科医生处就诊的各人群组中的风险因素患病率。本研究的目的是确定南非全科医疗人群中中风风险因素的患病率。
我们对南非全科医疗就诊患者进行了一项多中心观察性研究。从药品代表提供的名单中随机选择了200家全科诊所。每位全科医生连续接触50名30岁及以上的患者。患者填写了一份信息表,全科医生记录了患者的风险因素。所得样本即使在统计学意义上不一定具有代表性,但也是相关的。
在可能的10000份问卷中,共收回9731份。参与者的平均年龄为50.7岁。76%的人有1种或更多风险因素,40%的人有2种或更多风险因素。高血压是所有人群组中最常见的风险因素(55%),但在黑人患者中最高(59%)。血脂异常在白人中最常见(37%),在黑人中最不常见(5%)。糖尿病在亚洲人中最常见(24%),在白人中最不常见(8%)。除吸烟外的风险因素随年龄增加。
本研究提供了关于南非全科医疗人群中中风风险因素患病率的独特数据。风险因素在所有人群组中都很常见,但在各人群组中的分布有所不同。通过全科医生对风险因素的筛查和治疗,南非有很大机会减轻中风负担。