过氧阿卡诺酸酯A和D的全合成：金属介导的偶联反应作为合成多不饱和过氧化物的汇聚方法

Total synthesis of peroxyacarnoates A and D: metal-mediated couplings as a convergent approach to polyunsaturated peroxides.

作者信息

Xu Chunping, Raible Joseph M, Dussault Patrick H

机构信息

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska 68588-0304, USA.

出版信息

Org Lett. 2005 Jun 9;7(12):2509-11. doi: 10.1021/ol050291m.

DOI:10.1021/ol050291m

PMID:15932235

Abstract

[reaction: see text] The first syntheses of peroxyacarnoates A and D, members of a family of enyne-containing alkoxydioxanes, have been achieved on the basis of chemoselective ozonolysis within a polyunsaturated framework and Pd-mediated cross-couplings of a functionalized 1,2-dioxane.

摘要

[反应：见正文] 基于多不饱和骨架内的化学选择性臭氧分解以及功能化1,2 - 二氧六环的钯介导交叉偶联反应，实现了过氧阿卡诺酸酯A和D（含烯炔的烷氧基二氧六环家族的成员）的首次合成。