Slovut David P, Olin Jeffrey W
The Zena and Michael A. Wiener Cardiovascular Institute, Mount Sinai School of Medicine,One Gustave L. Levy Place, Box 1033,New York,NY 10029-6574,USA.
Curr Treat Options Cardiovasc Med. 2005 Jun;7(2):159-169. doi: 10.1007/s11936-005-0017-z.
The most common clinical manifestations of fibromuscular dysplasia (FMD) are hypertension due to renal artery involvement and transient ischemic attack or stroke due to carotid or vertebral artery involvement. Patients with renal artery FMD and hypertension should undergo primary angioplasty with the goal of curing the hypertension. If the blood pressure fails to normalize following angioplasty, the physician should institute antihypertensive medications according to the recommendations of the Joint National Committee on the Prevention, Detection, and Treatment of High Blood Pressure VII. In patients with cerebrovascular FMD, antiplatelet agents represent the cornerstone of therapy. Percutaneous angioplasty has emerged as the preferred treatment for symptomatic cerebrovascular FMD.
纤维肌性发育异常(FMD)最常见的临床表现是因肾动脉受累导致的高血压,以及因颈动脉或椎动脉受累导致的短暂性脑缺血发作或中风。患有肾动脉FMD和高血压的患者应接受以治愈高血压为目标的初次血管成形术。如果血管成形术后血压未能恢复正常,医生应根据美国国家高血压预防、检测、评估与治疗联合委员会第七次报告的建议使用抗高血压药物。对于患有脑血管FMD的患者,抗血小板药物是治疗的基石。经皮血管成形术已成为有症状脑血管FMD的首选治疗方法。