Wiegertjes Geert F, Forlenza Maria, Joerink Maaike, Scharsack Jörn P
Cell Biology and Immunology Group, Department of Animal Sciences, Wageningen Institute of Animal Sciences, Wageningen University, PO Box 338, Wageningen AH 6700, The Netherlands.
Dev Comp Immunol. 2005;29(9):749-58. doi: 10.1016/j.dci.2005.01.005. Epub 2005 Mar 7.
Studying parasites helps reveal basic mechanisms in immunology. For long this has been recognized for studies on the immune system of mice and man. But it is not true for immunological studies on fish. To support this argument we discuss selected examples of parasite infections not only in warm-blooded but also in cold-blooded vertebrates. We point out that parasite infections deserve more attention as model systems in comparative immunology.
研究寄生虫有助于揭示免疫学的基本机制。长期以来,这一点在对小鼠和人类免疫系统的研究中已得到认可。但在鱼类免疫学研究中并非如此。为支持这一观点,我们不仅讨论了温血脊椎动物,也讨论了冷血脊椎动物中寄生虫感染的选定实例。我们指出,在比较免疫学中,寄生虫感染作为模型系统应得到更多关注。