Seed Patrick C, Hultgren Scott J
Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Trends Microbiol. 2005 Jun;13(6):246-8. doi: 10.1016/j.tim.2005.03.014.
Recent work has shown how comparative genomic and microarray analyses can provide insights into the transcriptional state of uropathogenic Escherichia coli (UPEC) during infection. This study will serve as an important platform from which to identify virulence determinants and the principle mechanisms of adaptation to the urinary tract.
近期的研究工作已表明，比较基因组分析和微阵列分析如何能够为了解尿路致病性大肠杆菌（UPEC）在感染期间的转录状态提供见解。这项研究将成为一个重要平台，用以识别毒力决定因素以及适应泌尿道的主要机制。
