Weisberg Fay, Bouchard Céline, Moreau Michèle, Audet Marie Claude, Mawdsley Scott, Dattani Dan, Dinniwell Julie, Horbay G L A
Department of Obstetrics and Gynaecology, University of Toronto, Toronto ON.
J Obstet Gynaecol Can. 2005 Apr;27(4):350-9. doi: 10.1016/s1701-2163(16)30462-5.
To document Canadian women's experience with the transdermal contraceptive patch, a method delivering 150 microg norelgestromin and 20 microg ethinyl estradiol daily.
We conducted an open-label, multicentre, descriptive cohort study of the contraceptive patch over 9 cycles in 392 women requiring contraception. A single treatment cycle consisted of 3 consecutive 7-day patch applications followed by 1 patch-free week. At the final visit, overall satisfaction and preference for the patch was rated and compared with the previously used contraceptive method.
At baseline, 80.9% of participants were either very satisfied or somewhat satisfied with their previous contraceptive method, 89% having used oral contraceptives. At final observation, 60.6% of participants preferred the patch, 9.3% had no preference; and 30% preferred their previous method (n = 376). A total of 279 participants (71.2%) completed 9 cycles of patch use. Of these, 91% were satisfied with the patch and 74.9% preferred the patch to their previous contraceptive (43% strongly preferred and 31.9% preferred); 9% had no preference; and 16.1% preferred their previous method. Of those who preferred the patch, 82.7% preferred it because of its convenience or simplicity. Across all cycles, 88% of participants recorded perfect compliance. The most common adverse event was application site reactions (most of which were mild), experienced by 49% of participants: 33.7%, 16.5%, and 14.7% at cycles 1, 4, and 9, respectively.
Both preference for and satisfaction with the transdermal contraceptive patch were high. Most participants.
记录加拿大女性使用经皮避孕贴的体验，该方法每日释放150微克诺孕酯和20微克炔雌醇。
我们对392名需要避孕的女性进行了一项开放标签、多中心、描述性队列研究，观察她们在9个周期内使用避孕贴的情况。一个治疗周期包括连续3次7天的贴剂使用，然后是1周的无贴剂期。在最后一次随访时，对避孕贴的总体满意度和偏好进行评分，并与之前使用的避孕方法进行比较。
基线时，80.9%的参与者对其之前的避孕方法非常满意或 somewhat 满意，89%使用过口服避孕药。在最终观察时，60.6%的参与者更喜欢避孕贴，9.3%没有偏好；30%更喜欢她们之前的方法（n = 376）。共有279名参与者（71.2%）完成了9个周期的避孕贴使用。其中，91%对避孕贴满意，74.9%比她们之前的避孕方法更喜欢避孕贴（43%强烈更喜欢，31.9%更喜欢）；9%没有偏好；16.1%更喜欢她们之前的方法。在那些更喜欢避孕贴的人中，82.7%是因为其方便或简单而更喜欢它。在所有周期中，88%的参与者记录了完全依从性。最常见的不良事件是应用部位反应（大多数为轻度），49%的参与者经历过：在第1、4和9周期分别为33.7%、16.5%和14.7%。
对经皮避孕贴的偏好和满意度都很高。大多数参与者。 （注：原文最后一句不完整，已按完整内容翻译）
