Tokunaka S, Fujii H, Okamura K, Miyata M, Yachiku S
Department of Urology, Asahikawa Medical College.
Nihon Hinyokika Gakkai Zasshi. 1992 Apr;83(4):493-7. doi: 10.5980/jpnjurol1989.83.493.
The proportion of fast and slow myosin molecules in external urethral sphincter (EUS) was studied. The contents of fast and slow myosin light chains in EUS from 6 female rabbits (Japanese White, 6-month-old) were estimated using two-dimensional electrophoresis. The percentages of fast and slow myosin molecules were 54.5 +/- 14.9 and 46.0 +/- 14.9, respectively. It was thus shown that female rabbits EUS is composed of both fast and slow muscle fibers. The ratio of fast to slow myosins in female EUS was different from that in male EUS (fast myosin 90%). These results implicate that female and male EUS would be functionally distinct.
研究了雌性兔尿道外括约肌（EUS）中快肌球蛋白和慢肌球蛋白分子的比例。使用二维电泳法对6只雌性日本白兔（6月龄）EUS中的快肌球蛋白轻链和慢肌球蛋白轻链含量进行了测定。快肌球蛋白分子和慢肌球蛋白分子的百分比分别为54.5±14.9和46.0±14.9。由此表明，雌性兔EUS由快肌纤维和慢肌纤维组成。雌性EUS中快肌球蛋白与慢肌球蛋白的比例与雄性EUS（快肌球蛋白占90%）不同。这些结果表明，雌性和雄性EUS在功能上可能存在差异。
