von Giesen Hans-Jürgen, Haslinger Bernhard A, Rohe Simone, Köller Hubertus, Arendt Gabriele
Department of Neurology, Heinrich Heine University Düsseldorf, Germany.
J Neuropsychiatry Clin Neurosci. 2005 Spring;17(2):185-91. doi: 10.1176/jnp.17.2.185.
The authors examined the correlation between Human Immunodeficiency Virus (HIV) Dementia Scale (HDS) and psychomotor tests, evaluating basal ganglia function in 266 HIV-seropositive, Caucasian, homosexual men. Fifty-five HIV-positive, patients with mild dementia (HDS score < or =10) showed significant slowing of most rapid alternating movements (MRAM) and significantly prolonged contraction times compared to 211 HIV-positive nondemented patients (HDS score >10). Motor performance correlated significantly with the time-dependent HDS subscores for psychomotor speed and construction and HDS sum score. In contrast to contraction times and MRAM, HDS scores also showed significant correlations to age, premorbid and actual intelligence, and duration of HIV seropositivity.
作者研究了人类免疫缺陷病毒(HIV)痴呆量表(HDS)与精神运动测试之间的相关性,评估了266名HIV血清反应阳性的白人同性恋男性的基底神经节功能。与211名HIV阳性无痴呆患者(HDS评分>10)相比,55名HIV阳性轻度痴呆患者(HDS评分≤10)表现出大多数快速交替运动(MRAM)显著减慢,收缩时间显著延长。运动表现与精神运动速度和结构的时间依赖性HDS子评分以及HDS总分显著相关。与收缩时间和MRAM不同,HDS评分还与年龄、病前和实际智力以及HIV血清反应阳性持续时间显著相关。