ζ-电位和尺寸阶跃变化的毛细管接头处电渗流特性分析

Analysis of electro-osmotic flow characteristics at joint of capillaries with step change in zeta-potential and dimension.

作者信息

Ruijin Wang, Jianzhong Lin, Zhihua Li

机构信息

Department of Mechanics, State Key Laboratory of Fluid Power Transmission and Control, Zhejiang University, Hangzhou 310027, PR China.

出版信息

Biomed Microdevices. 2005 Jun;7(2):131-5. doi: 10.1007/s10544-005-1592-1.

DOI:10.1007/s10544-005-1592-1

PMID:15940427

Abstract

The Navier-Stokes equation was used to describe the characteristics of electro-osmotic flow. The corresponding numerical simulations were performed for varying zeta-potential and dimension. The results indicated that a step change in zeta-potential will cause a significant variation in the velocity profile and pressure distribution of the flow. A step change both in zeta-potential and dimension will result in a more violent variation near the joint of the capillary. This variation will reduce the separation efficiency and quality of capillary electrophoresis. The conclusions are helpful to design and fabrication of microfluidic devices, the analysis of data collected from such devices and improvement of the separation efficiency of capillary electrophoresis.

摘要

采用纳维-斯托克斯方程来描述电渗流的特性。针对不同的zeta电位和尺寸进行了相应的数值模拟。结果表明，zeta电位的阶跃变化会导致流动的速度分布和压力分布发生显著变化。zeta电位和尺寸的阶跃变化都会在毛细管接头附近导致更剧烈的变化。这种变化会降低毛细管电泳的分离效率和质量。这些结论有助于微流控器件的设计与制造、对此类器件所收集数据的分析以及毛细管电泳分离效率的提高。