Levine James W, Gota Carmen, Fessler Barri J, Calabrese Leonard H, Cooper Sheldon M
Rheumatology and Clinical Immunology Division, University of Vermont College of Medicine, Burlington, Vermont 05405, USA.
J Rheumatol. 2005 Jun;32(6):1164-7.
There is a well established link between type II mixed cryoglobulinemia (MC) and hepatitis C virus (HCV) infection, and HCV is believed to be the cause of cryoprotein formation and tissue deposition. Successful treatment of HCV infection has resulted in resolution of cryoglobulinemia and vasculitis. We describe 4 patients who had persistent MC and vasculitis despite successful eradication of HCV with antiviral therapy.
II型混合性冷球蛋白血症（MC）与丙型肝炎病毒（HCV）感染之间存在着已被充分证实的联系，并且HCV被认为是冷球蛋白形成和组织沉积的原因。HCV感染的成功治疗已使冷球蛋白血症和血管炎得到缓解。我们描述了4例患者，尽管通过抗病毒治疗成功根除HCV，但仍存在持续性MC和血管炎。
