开发一种结合程序升温进样口柱上进样的气相色谱-质谱联用高灵敏度定量分析方法来测定聚氨基甲酸酯。

Development of a high-sensitivity quantitative analytical method for determining polycarbamate by gas chromatography-mass spectrometry incorporating temperature-programmable inlet on-column injection.

作者信息

Kawamoto Tatsuhiko, Yano Miho, Makihata Nobuko

机构信息

Hyogo Prefectural Institute of Public Health and Environmental Sciences, 2-1-29, Arata-cho, Hyogo-ku, Kobe 652-0032, Japan.

出版信息

J Chromatogr A. 2005 May 13;1074(1-2):155-61. doi: 10.1016/j.chroma.2005.03.076.

DOI:10.1016/j.chroma.2005.03.076

PMID:15941051

Abstract

A highly sensitive analytical method was developed using GC/MS with temperature-programmable inlet on-column injection (TPI on-column GC/MS) for determining methyl dimethyldithiocarbamate (DMDC-methyl) and dimethyl ethylenebisdithiocarbamate (EBDC-dimethyl), which are methyl derivatives of alkali decomposed polycarbamate. This method makes it possible to quantify 0.3 microg/l of polycarbamate in tap water, which is a 1/100 of the residual target value of 30 microg/l in Japan. Moreover, it now becomes possible to distinguish polycarbamate from other dithiocarbamate pesticides (DTCs) that have similar structures, including ziram and thiram, which only incorporate a DMDC side chain, or manzeb, maneb and zineb, which only incorporate an EBDC side chain, by simultaneously analyzing for DMDC-methyl and EBDC-dimethyl.

摘要

开发了一种高灵敏度分析方法，采用带程序升温进样口的柱上进样气相色谱/质谱联用仪（柱上进样气相色谱/质谱联用仪）来测定甲基二甲基二硫代氨基甲酸盐（DMDC-甲基）和二甲基亚乙基双二硫代氨基甲酸盐（EBDC-二甲基），它们是碱分解聚氨基甲酸盐的甲基衍生物。该方法能够对自来水中0.3微克/升的聚氨基甲酸盐进行定量，这是日本30微克/升残留目标值的1/100。此外，通过同时分析DMDC-甲基和EBDC-二甲基，现在能够将聚氨基甲酸盐与其他结构相似的二硫代氨基甲酸盐农药（DTCs）区分开来，这些农药包括仅含有DMDC侧链的福美锌和福美双，或仅含有EBDC侧链的代森锰锌、代森锰和代森锌。