Harden R Norman, Weinland Stephan R, Remble Thomas A, Houle Timothy T, Colio Sean, Steedman Susan, Kee William G
Center for Pain Studies, Rehabilitation Institute of Chicago, Chicago, Illinois 60611, USA.
J Pain. 2005 Jun;6(6):364-71. doi: 10.1016/j.jpain.2005.01.350.
The Medication Quantification Scale (MQS) is an instrument with potential clinical and research applications for quantifying medication regimen use in chronic pain populations. The MQS was developed in 1992 and updated in 1998 (MQS II) as a tool to co-quantify 3 relevant aspects of medications prescribed for chronic nonmalignant pain: drug class, dosage, and detriment (risk). This 2003 version (MQS III) is the third iteration of the scale, featuring new detriment weights determined by surveying all physician members of the American Pain Society in the United States via mail. A total of 248 physicians (18%) responded with their opinion as to the detriment of 22 mechanistically distinct medication classes. Overall, the physician ratings of detriment weight were relatively consistent (alpha = .84). The increased number of survey responses encompassed a wide range of disciplines, thus reducing discipline bias and introducing several important changes to MQS scoring. Some medication classes previously rated with low detriment weights (eg, nonsteroidal anti-inflammatory drugs) increased in detriment weight (from 2 to 3.4), whereas other classes previously given high weights (eg, "strong" opioids) received lower detriment ratings (from 5 to 3.4) in this survey. The MQS III must now be validated in clinical and research applications.
The MQS is a tool to objectively quantify pain. It computes a single numeric value for a patient's pain medication profile. This number can be used by both clinicians and researchers to track pain levels through a treatment course or research study.
药物量化量表(MQS)是一种在慢性疼痛人群中具有潜在临床和研究应用价值的工具,用于量化药物治疗方案的使用情况。MQS于1992年开发,并于1998年更新为MQS II,作为一种共同量化慢性非恶性疼痛所开药物三个相关方面的工具:药物类别、剂量和损害(风险)。2003年版(MQS III)是该量表的第三次迭代,其特点是通过邮件调查美国疼痛协会的所有医生成员确定了新的损害权重。共有248名医生(18%)回复了他们对22种机制上不同药物类别的损害意见。总体而言,医生对损害权重的评分相对一致(α = 0.84)。增加的调查回复涵盖了广泛的学科,从而减少了学科偏差,并对MQS评分引入了一些重要变化。一些之前损害权重评分较低的药物类别(如非甾体抗炎药)损害权重增加(从2增加到3.4),而其他之前权重较高的类别(如“强效”阿片类药物)在本次调查中获得了较低的损害评分(从5降至3.4)。现在必须在临床和研究应用中对MQS III进行验证。
MQS是一种客观量化疼痛的工具。它为患者的疼痛药物概况计算一个单一数值。临床医生和研究人员都可以使用这个数字来跟踪治疗过程或研究中的疼痛水平。