一项针对美国儿科麻醉医师的全国性调查:小儿急性疼痛管理中的患者自控镇痛和其他静脉内阿片类药物治疗。

A national survey of American Pediatric Anesthesiologists: patient-controlled analgesia and other intravenous opioid therapies in pediatric acute pain management.

机构信息

Department of Anesthesiology and Critical Care Medicine, Division of Pediatric Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

出版信息

Anesth Analg. 2010 Mar 1;110(3):754-60. doi: 10.1213/ANE.0b013e3181ca749c.

Abstract

BACKGROUND

The influence of patient characteristics, institutional demographics, and published practice guidelines on the provision of IV opioid analgesia, particularly as delivered through a patient-controlled analgesia (PCA) delivery device, to pediatric patients is unknown.

METHODS

We sent a national, web-based, descriptive survey of pediatric pain management practice to select members of the Society for Pediatric Anesthesia to assess institutional demographics, availability and implementation of IVPCA and PCA by proxy, and recalled occurrence of serious and life-threatening opioid-related side effects.

RESULTS

Data from respondents at 252 institutions throughout the United States were collected and analyzed. Sixty-nine percent of respondents practiced in a children's hospital or children's center within a general hospital, and 51% of institutions had a pediatric pain service. Virtually all pediatric pain services (91%) were administered by departments of anesthesiology. Pediatric pain service availability correlated with the number of pediatric beds. IVPCA was available to pediatric patients at 96% of institutions surveyed, whereas IVPCA by proxy was available at only 38%. Eleven percent of respondents reported that their hospital no longer provided IVPCA by proxy as a result of the 2004 Joint Commission on Accreditation of Hospitals Sentinel Event Warning. Instructional material concerning IVPCA was provided to patients or their families by 40% of institutions. IVPCA orders were handwritten by 55% of respondents, despite 39% having computerized provider order entry systems. Ninety percent of respondents reported using pulse oximetry monitoring when patients were administered IVPCA. Forty-two respondents recalled patients having received naloxone to counteract the cardiopulmonary side effects of opioids during the year before receipt of the survey. Eight respondents recalled patient deaths having occurred over the past 5 years in patients receiving IVPCA, IVPCA by proxy, and continuous non-IVPCA opioid infusions.

CONCLUSIONS

Although IVPCA was available to pediatric patients at most institutions surveyed, prescribing practices and supervision of pediatric pain management were influenced by patient characteristics, institutional demographics, and published national guidelines. Recalled life-threatening events were reported in conjunction with all modes of opioid infusion therapy. Interventions that might diminish the incidence of adverse events but are not used to their fullest extent include improved education and implementation of systems designed to minimize human error involved in the prescribing of opioids. Providing a more accurate accounting of complications would require institutions to participate in a prospective data-collecting consortium designed to track both the incidence of therapy and associated complications.

摘要

背景

目前尚不清楚患者特征、机构人口统计学特征以及已发布的实践指南对小儿患者静脉注射阿片类药物镇痛(尤其是通过患者自控镇痛(PCA)给药装置给药)的影响。

方法

我们向选择的美国儿科学会麻醉分会成员发送了一项全国性的网络描述性小儿疼痛管理实践调查,以评估机构人口统计学特征、IVPCA 和代理 PCA 的可用性和实施情况,以及回忆严重和危及生命的阿片类相关副作用的发生情况。

结果

对来自美国 252 家机构的应答者数据进行了收集和分析。69%的应答者在儿童医院或综合医院内的儿童中心执业,51%的机构设有小儿疼痛服务。几乎所有的小儿疼痛服务(91%)均由麻醉科管理。96%的调查机构可为小儿患者提供 IVPCA,而仅有 38%的机构提供代理 IVPCA。11%的应答者报告称,由于 2004 年联合委员会发布的医院警戒事件警告,其所在医院不再提供代理 IVPCA。40%的机构向患者或其家属提供 IVPCA 的指导材料。尽管 39%的机构有计算机化医嘱输入系统,但 55%的应答者仍手写 IVPCA 医嘱。90%的应答者报告在给患者使用 IVPCA 时进行脉搏血氧饱和度监测。42 位应答者在调查前一年曾回忆患者接受纳洛酮以对抗阿片类药物的心肺副作用。8 位应答者回忆在过去 5 年中,在接受 IVPCA、代理 IVPCA 和连续非-IVPCA 阿片类药物输注的患者中,有 8 例患者死亡。

结论

尽管大多数接受调查的机构都可为小儿患者提供 IVPCA,但小儿疼痛管理的处方实践和监管受到患者特征、机构人口统计学特征和已发布的国家指南的影响。在所有模式的阿片类药物输注治疗中,都报告了危及生命的不良事件。尚未充分利用但可能减少不良事件发生率的干预措施包括改善教育和实施旨在最小化开具阿片类药物时人为错误的系统。提供更准确的并发症报告将需要机构参与旨在跟踪治疗和相关并发症发生率的前瞻性数据收集联盟。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索