Gualco Gabriela, Ortega Virginia, Ardao Gonzalo, Cravioto Fernando
Department of Pathology, Central Armed Forces Hospital, Montevideo, MDEO 11600, Uruguay.
Ann Diagn Pathol. 2005 Jun;9(3):153-6. doi: 10.1016/j.anndiagpath.2005.02.006.
We present a case of a 16-year-old boy with a primary clear cell adenocarcinoma of the prostatic utricle. The patient presented with a 6-month history of intermittent, nonpainful, gross hematuria and an associated right renal agenesis. Radiographic studies revealed the presence of a solid and cystic mass between the bladder neck and the cranium of the prostate. Serum tests, including prostate-specific antigen, carcinoembryonic antigen, CA-19-9, and human chorionic gonadotropin, were performed and found to be within normal limits. A surgical resection of the mass including prostate and seminal vesicles was performed. Grossly, a polypoid exophytic tumor was present at the prostatic utricle. Histologically, the tumor shows the classical clear cell morphology reminiscent of the so-called mesonephric adenocarcinomas. At clinical follow-up, the patient is alive and well 18 months after surgical resection. The present case highlights an unusual phenomenon of the development of an unusual form of adenocarcinoma in an adolescent.
我们报告一例16岁男性原发性前列腺囊透明细胞腺癌病例。该患者有6个月间歇性、无痛性肉眼血尿病史，伴有右肾缺如。影像学检查显示膀胱颈与前列腺头之间存在实性和囊性肿块。进行了包括前列腺特异性抗原、癌胚抗原、CA - 19 - 9和人绒毛膜促性腺激素在内的血清检查，结果均在正常范围内。对包括前列腺和精囊的肿块进行了手术切除。大体上，前列腺囊处有一个息肉样外生性肿瘤。组织学上，肿瘤呈现出典型的透明细胞形态，让人联想到所谓的中肾腺癌。临床随访时，患者在手术切除18个月后仍存活且状况良好。本病例凸显了青少年发生一种不寻常形式腺癌的罕见现象。
