Ahroni Jessie H, Montgomery Kevin F, Watkins Brad M
Department of Biobehavioral Nursing and Health Systems, School of Nursing, University of Washington, Seattle, WA, USA.
Obes Surg. 2005 May;15(5):641-7. doi: 10.1381/0960892053923716.
The objective of this study was to determine the weight loss, changes in co-morbidities, medication usage and general health status at 1 year after laparoscopic adjustable gastric banding (LAGB).
Prospective data were obtained from all subjects undergoing LAGB. These measurements included a medical history and review of systems, medications, height and weight and the SF-36 general health survey. Patients were seen for band adjustments as needed throughout the year. At the 1-year follow-up visit, patients were weighed and interviewed about the status of their health conditions and their current medications, and the SF-36 was repeated.
Between November 2002 and November 2003, 195 patients had LAGB. The majority of subjects were female (82.8%), married (65.1%), and white (94.9%). Complications occurred in 18 subjects (9.2%). These included 3 slipped bands (1.5%), 4 port problems (2.1%), 8 patients with temporary stoma occlusion (4.1%), 1 explantation (0.5%), and 1 mortality (0.5%). Mean BMI decreased from 45.8 kg/m2 (+/- 7.7) to 32.3 kg/m2 (+/- 7.0). Mean percent excess body weight lost was 45.7% (+/- 17.1) during the first year. Major improvements occurred in arthritis, asthma, depression, diabetes, gastro-esophageal reflux disease, hyperlipidemia, hypertension, joint and back pain, sleep apnea and stress incontinence. Medication usage declined remarkably. Quality of life (QoL) by the SF-36 showed highly significant improvements.
At 1 year after LAGB, patients had experienced significant weight loss, resolution of comorbidities, decreases in medication usage, and improvements in QoL.
本研究的目的是确定腹腔镜可调节胃束带术（LAGB）术后1年时的体重减轻情况、合并症变化、药物使用情况及总体健康状况。
前瞻性收集所有接受LAGB手术患者的数据。这些测量包括病史、系统回顾、用药情况、身高和体重以及SF-36总体健康调查。全年根据需要对患者进行束带调整。在1年随访时，对患者进行称重，并询问其健康状况和当前用药情况，再次进行SF-36调查。
2002年11月至2003年11月期间，195例患者接受了LAGB手术。大多数受试者为女性（82.8%）、已婚（65.1%）、白人（94.9%）。18例受试者（9.2%）出现并发症。其中包括3例束带滑脱（1.5%）、4例端口问题（2.1%）、8例患者出现临时造口阻塞（4.1%）、1例取出束带（0.5%）和1例死亡（0.5%）。平均体重指数从45.8kg/m²（±7.7）降至32.3kg/m²（±7.0）。第一年平均额外体重减轻百分比为45.7%（±17.1）。关节炎、哮喘、抑郁症、糖尿病、胃食管反流病、高脂血症、高血压、关节和背痛、睡眠呼吸暂停和压力性尿失禁均有显著改善。药物使用显著减少。SF-36显示生活质量（QoL）有高度显著改善。
LAGB术后1年，患者体重显著减轻，合并症得到缓解，药物使用减少，生活质量得到改善。
