Raaijmakers L C H, Pouwels S, Thomassen S E M, Nienhuijs S W
Department of Surgery, Catharina Hospital, Eindhoven, The Netherlands.
Eur J Clin Nutr. 2017 Apr;71(4):441-449. doi: 10.1038/ejcn.2016.198. Epub 2016 Nov 2.
Currently the effects of bariatric surgery are generally expressed in excess weight loss or comorbidity reduction. Therefore the aim of this review was to provide insight in the available prospective evidence regarding the short and long-term effects of bariatric surgery on Quality of Life (QoL) and a comparison with community norms. A systematic multi-database search was conducted for 'QoL' and 'Bariatric surgery'. Only prospective studies with QoL before and after bariatric surgery were included. The 'Quality Assessment Tool for Before-After Studies with No Control Group' was used to assess the methodological quality. Thirty-six studies met the inclusion criteria. Most studies were assessed to be of 'fair' to 'good' methodological quality. Ten different questionnaires were used to measure QoL. Follow-up ranged from 6 months to 10 years, sample sizes from 26 to 1276 and follow-up rates from 45 to 100%. A significant increase in QoL after bariatric surgery was found in all studies (P⩽0.05), however, mostly these outcomes stay below community norms. Only outcomes of the IWQoL, SF-36 and OWQoL show QoL outcomes that exceed community norms. The QoL is increased after bariatric surgery on both the short and long term. However, due to the heterogeneity of the studies and the generality of the questionnaires is it hard to make a distinction between different surgeries and difficult to see a relation with medical profit. Therefore, tailoring QoL measurements to the bariatric population is recommended as the focus of future studies.
目前,减肥手术的效果通常用超重减轻或合并症减少来表示。因此,本综述的目的是深入了解关于减肥手术对生活质量(QoL)的短期和长期影响的现有前瞻性证据,并与社区标准进行比较。对“QoL”和“减肥手术”进行了系统的多数据库搜索。仅纳入了有减肥手术前后QoL的前瞻性研究。使用“无对照组前后研究质量评估工具”来评估方法学质量。三十六项研究符合纳入标准。大多数研究被评估为方法学质量“中等”至“良好”。使用了十种不同的问卷来测量QoL。随访时间从6个月到10年不等,样本量从26到1276不等,随访率从45%到100%不等。所有研究均发现减肥手术后QoL有显著提高(P⩽0.05),然而,这些结果大多仍低于社区标准。只有IWQoL、SF - 36和OWQoL的结果显示QoL结果超过社区标准。减肥手术后短期和长期的QoL均有所提高。然而,由于研究的异质性和问卷的通用性,很难区分不同的手术,也难以看出与医学获益的关系。因此,建议将针对减肥人群的QoL测量作为未来研究的重点。