El Mouzan Mohammad Issa, Abdullah Asaad Mohammad, Al Habbal Mohammad Talal
J Trop Pediatr. 2006 Feb;52(1):69-71. doi: 10.1093/tropej/fmi039. Epub 2005 Jun 9.
There is limited information about inflammatory bowel disease in Arab children. Hence, the objective of this study was to report on the epidemiology of this condition in our community. Medical records were analysed for all children below 18 years of age diagnosed with inflammatory bowel disease (IBD) and followed up in our institution over a period of 10 years. From 1993 to 2002, 50 consecutive children were diagnosed to have IBD. This gives an estimated incidence of 0.5 cases/100 000/year and a prevalence of 5 cases/100 000 populations for the region of Riyadh, Saudi Arabia. Most of the children (90 per cent) were Saudi nationals and the female to male ratio was 1 : 0.6. The age range was between 5 and 18 years with 16 per cent of the cases diagnosed in children below 12 years of age. Chronic ulcerative colitis was the commonest form accounting for 48 per cent, followed by Crohn's disease and indeterminate colitis in 38 per cent and 16 per cent of the children, respectively. The best agreement between colonoscopic and histopathologic findings (89 per cent) was in children with ulcerative colitis followed by normal findings and Crohn's disease in 63 per cent and 35 per cent of the cases, respectively. It was concluded that the incidence and prevalence of IBD in this report are lower than in any other population. Nevertheless, comparison with older data suggests that the incidence is increasing.
关于阿拉伯儿童炎症性肠病的信息有限。因此，本研究的目的是报告我们社区中这种疾病的流行病学情况。对在我们机构接受随访的所有18岁以下被诊断为炎症性肠病（IBD）的儿童的病历进行了分析，随访时间为10年。从1993年到2002年，连续有50名儿童被诊断患有IBD。这表明沙特阿拉伯利雅得地区的估计发病率为0.5例/10万/年，患病率为5例/10万人口。大多数儿童（90%）是沙特公民，男女比例为1:0.6。年龄范围在5岁至18岁之间，16%的病例是在12岁以下的儿童中诊断出来的。慢性溃疡性结肠炎是最常见的类型，占48%，其次是克罗恩病和不确定性结肠炎，分别占儿童病例的38%和16%。结肠镜检查和组织病理学检查结果之间的最佳一致性（89%）出现在溃疡性结肠炎患儿中，其次是正常结果和克罗恩病，分别占病例的63%和35%。得出的结论是，本报告中IBD的发病率和患病率低于其他任何人群。然而，与早期数据相比表明发病率正在上升。
