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一名白血病患者因烟曲霉样拟青霉引发致命肺部感染。

Fatal pulmonary infection in a leukaemic patient caused by Hormographiella aspergillata.

作者信息

Lagrou Katrien, Massonet Caroline, Theunissen Koen, Meersseman Wouter, Lontie Marc, Verbeken Eric, Van Eldere Johan, Maertens Johan

机构信息

Immunology and Microbiology1, Hematology2, Internal Medicine3 and Pathology5, University Hospital Leuven, Herestraat 49, 3000 Leuven, Belgium 4Laboratory for Microbiology, MCH, Maria Theresiastraat 63A, 3000 Leuven, Belgium.

出版信息

J Med Microbiol. 2005 Jul;54(Pt 7):685-688. doi: 10.1099/jmm.0.46016-0.

DOI:10.1099/jmm.0.46016-0
PMID:15947435
Abstract

A case of autopsy-proven fungal pneumonia in a relapsed leukaemia patient is reported. The fungus Hormographiella aspergillata was cultured from two bronchoalveolar fluid samples and identified through morphological examination and ITS2 sequence analysis. In addition, galactomannan was detected in eight consecutive serum samples, which suggested a co-infection with Aspergillus species. The patient was treated with caspofungin.

摘要

报告了一例经尸检证实的复发性白血病患者真菌性肺炎病例。从两份支气管肺泡灌洗样本中培养出曲霉状拟青霉,并通过形态学检查和ITS2序列分析进行鉴定。此外,在连续八份血清样本中检测到半乳甘露聚糖,提示同时感染曲霉菌属。该患者接受了卡泊芬净治疗。

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