Bocciardi Aldo, Lesma Arianna, Montorsi Francesco, Rigatti Patrizio
Department of Urology, Vita-Salute University, San Raffaele Hospital, Milan, Italy.
J Urol. 2005 Jul;174(1):284-8; discussion 288. doi: 10.1097/01.ju.0000161211.40944.87.
We report our experience with early 1-stage Passerini-Glazel feminizing genitoplasty with special emphasis on long-term results of vaginoplasty.
A total of 66 patients with ambiguous genitalia underwent 1-stage Passerini-Glazel feminizing genitoplasty. Long-term followup included an outpatient visit at 1 year postoperatively and a genital assessment with the patient under general anesthesia performed before menarche courses in those operated on at age 6 months to 8 years, and at 2 years postoperatively for those operated on at 9 years or older.
All patients underwent the first long-term followup evaluation and no major complications were observed. The second long-term followup evaluation was performed in 46 patients (70%). In all cases the vaginal introitus was located in the physiological position and was large and elastic. Vaginal caliber at the suture line between the tubularized flap and vaginal mucosa was the same size as the vaginal introitus and distal native vagina in 20 of 46 patients (43%), slightly smaller in 10 (22%) and stenotic in 16 (35%). Stenosis at the suture line was corrected with simple Y-V introitoplasty performed at the same followup visit.
Early 1-stage Passerini-Glazel feminizing genitoplasty is a safe and effective procedure that allows total surgical correction of ambiguous genitalia in infancy and good cosmetic results. Incidence of vaginal stenosis at the suture line is high but it can be repaired with simple introitoplasty performed before menarche occurs. Good functional results are presumed.
我们报告早期一期帕塞里尼 - 格拉泽女性化生殖器成形术的经验，特别强调阴道成形术的长期效果。
共有66例生殖器模糊的患者接受了一期帕塞里尼 - 格拉泽女性化生殖器成形术。长期随访包括术后1年的门诊复查，以及对6个月至8岁接受手术的患者在月经初潮前进行全身麻醉下的生殖器评估，对9岁及以上接受手术的患者在术后2年进行评估。
所有患者均接受了首次长期随访评估，未观察到重大并发症。46例患者（70%）进行了第二次长期随访评估。在所有病例中，阴道口位于生理位置，宽大且有弹性。在46例患者中的20例（43%），管状皮瓣与阴道黏膜缝合线处的阴道口径与阴道口及远端原阴道大小相同，10例（22%）略小，16例（35%）狭窄。在同一次随访中通过简单的Y - V阴道口成形术纠正了缝合线处的狭窄。
早期一期帕塞里尼 - 格拉泽女性化生殖器成形术是一种安全有效的手术方法，可在婴儿期对生殖器模糊进行全面手术矫正，并获得良好的美容效果。缝合线处阴道狭窄的发生率较高，但可在月经初潮前通过简单的阴道口成形术修复。推测可获得良好的功能效果。
