醛固酮阻断在心力衰竭患者中的作用。
The role of aldosterone blockade in patients with heart failure.
作者信息
Pitt Bertram
机构信息
The University of Michigan School of Medicine, Ann Arbor, MI 48170, USA.
出版信息
Heart Fail Rev. 2005 Jan;10(1):79-83. doi: 10.1007/s10741-005-2352-2.
PMID:15947895
Abstract
The mechanisms associated with aldosterone production both systemically and locally as well as the effects of aldosterone blockade on the pathophysiology of heart failure (HF) have been extensively reviewed in this series and elsewhere. This article will review the clinical evidence supporting the use of aldosterone blocking agents (AB)in patients with HF and speculate on some potential future uses.
摘要
本系列文章及其他地方已对醛固酮在全身和局部产生的相关机制，以及醛固酮阻断对心力衰竭（HF）病理生理学的影响进行了广泛综述。本文将回顾支持在心力衰竭患者中使用醛固酮阻断剂（AB）的临床证据，并推测其未来一些潜在的用途。
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