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[在混合淋巴细胞培养中,对用冷盐治疗的类风湿性多关节炎患者淋巴细胞的同种异体反应性和抑制功能的研究]

[Study of the allogenic reactivity and suppression function of lymphocytes, in rheumatoid polyarthritis treated with cold salts, in mixed lymphocyte cultures].

作者信息

Roux H, Bonnefoy-Cudraz M, Iacono C, Mercier P, Peterhansel E

出版信息

Rev Rhum Mal Osteoartic. 1979 May;46(5):319-26.

PMID:159488
Abstract

In a group of 30 rheumatoid polyarthritis treated with gold salts, a determination of the T lymphocytes (sheep red cells) furnished in percentage normal values, and in absolute value a normal average value, with, however, a low level of T lymphocytes. In autologous lymphocyte cultures no spontaneous increase of DNA synthesis was registered. The allogenic response was normal, and in mixed culture with the addition of a third type of cells, a discrete specific suppressive activity appeared.

摘要

在一组接受金盐治疗的30例类风湿性多关节炎患者中,对T淋巴细胞(绵羊红细胞)的测定显示,其在百分比上为正常值,绝对值也处于正常平均水平,然而T淋巴细胞水平较低。在自体淋巴细胞培养中,未发现DNA合成的自发增加。同种异体反应正常,并且在添加第三种细胞类型的混合培养中,出现了离散的特异性抑制活性。

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