Fontaine K R, Heo M, Allison D B
Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Public Health. 2005 Aug;119(8):694-8. doi: 10.1016/j.puhe.2004.09.002. Epub 2005 Jan 19.
To estimate the association between body mass index (BMI: kg/m2) and prostate-specific antigen (PSA) cancer screening in a nationally representative sample of US men aged 50 years and older using data from the 2001 Behavioral Risk Factor Surveillance Survey.
Men aged 50 years or older classified by BMI as healthy weight range (18.5-24.9), overweight (25-29.9), obese class I (30-34.9), obese class II (35-39.9), and obese class III (> or =40).
Interval since most recent screening for PSA.
Adjusting for age, race, smoking, education, employment, income and health insurance status, we found that, compared with men in the healthy weight range, men in the overweight [odds ratio (OR)=1.13; 95% confidence interval (95% CI)=1.04-1.35], obese class I (OR=1.26; 95% CI=1.06-1.36) and obese class II (OR=1.14, 95% CI=1.02-1.26) categories were significantly more likely to have obtained a PSA test within the previous year. A similar pattern was observed when we examined other screening intervals (e.g. within past 2 years, within past 3 years, etc.).
Among men aged 50 years and older, overweight and obesity is associated with obtaining a PSA test.
利用2001年行为危险因素监测调查的数据，在美国50岁及以上男性的全国代表性样本中，评估体重指数（BMI：千克/平方米）与前列腺特异性抗原（PSA）癌症筛查之间的关联。
50岁及以上男性，根据BMI分为健康体重范围（18.5 - 24.9）、超重（25 - 29.9）、I类肥胖（30 - 34.9）、II类肥胖（35 - 39.9）和III类肥胖（≥40）。
距最近一次PSA筛查的时间间隔。
在对年龄、种族、吸烟、教育程度、就业情况、收入和健康保险状况进行调整后，我们发现，与健康体重范围内的男性相比，超重男性[比值比（OR）=1.13；95%置信区间（95%CI）=1.04 - 1.35]、I类肥胖男性（OR = 1.26；95%CI = 1.06 - 1.36）和II类肥胖男性（OR = 1.14，95%CI = 1.02 - 1.26）在前一年进行PSA检测的可能性显著更高。当我们检查其他筛查时间间隔（例如过去2年内、过去3年内等）时，也观察到了类似的模式。
在50岁及以上男性中，超重和肥胖与进行PSA检测有关。
