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有症状的肝脏巨大血管瘤的外科治疗

Surgical treatment of symptomatic giant hemangiomas of the liver.

作者信息

Belli L, De Carlis L, Beati C, Rondinara G, Sansalone V, Brambilla G

机构信息

Department of Surgery, Pizzamiglio 2 Niguarda Hospital, Milan, Italy.

出版信息

Surg Gynecol Obstet. 1992 Jun;174(6):474-8.

PMID:1595024
Abstract

Cavernous hemangiomas are the most common benign tumors of the liver. Twenty-four patients who had hepatic resections for giant symptomatic hepatic hemangiomas during a six year period at a single institute were retrospectively reviewed to analyze indications for surgical treatment and evaluate operative mortality and morbidity. There were 18 women and six men varying in age from 41 to 69 years with an average age of 52.5 years. Moderate to severe pain, discomfort, feeling of fullness, bloating and sensation of an abdominal mass were the most commonly reported symptoms. Ten patients had moderate anemia and two had severe anemia. Tumors were visualized by ultrasonography in all patients and by computed tomography in 18. Angiography was performed in all patients with diagnostic confirmation of a benign hemangioma in all but one patient in whom an angiosarcoma was suspected. The resection was feasible in each patient: 20 minor hepatic resections (three wedge, 11 segmentectomies, six bisegmentectomies) and four right hepatic lobectomies were carried out. There were no surgical deaths. Two patients had postoperative complications: one patient had a pneumonia on the right side and one had wound infection. The benign nature of the tumors was confirmed in all. The lesions varied in size from 5.6 to 26 centimeters in diameter. Symptoms and hematologic disorders were relieved in all patients in the follow-up. The results of our experience confirm that resection for giant symptomatic hepatic hemangioma represents a safe radical curative procedure. Medical treatment is justified in smaller lesions or in asymptomatic patients.

摘要

海绵状血管瘤是肝脏最常见的良性肿瘤。回顾性分析了在一所机构6年期间因巨大有症状肝血管瘤接受肝切除术的24例患者,以分析手术治疗的指征并评估手术死亡率和发病率。患者中有18名女性和6名男性,年龄在41至69岁之间,平均年龄为52.5岁。最常报告的症状为中度至重度疼痛、不适、饱胀感、腹胀和腹部肿块感。10例患者有中度贫血,2例有重度贫血。所有患者均通过超声检查发现肿瘤,18例通过计算机断层扫描发现。除1例怀疑为血管肉瘤的患者外,所有患者均进行了血管造影,所有患者均确诊为良性血管瘤。每位患者的切除手术均可行:进行了20例小肝切除术(3例楔形切除术、11例肝段切除术、6例双肝段切除术)和4例右肝叶切除术。无手术死亡病例。2例患者有术后并发症:1例患者发生右侧肺炎,1例患者发生伤口感染。所有肿瘤均证实为良性。病变直径从5.6厘米至26厘米不等。随访中所有患者的症状和血液学紊乱均得到缓解。我们的经验结果证实,切除巨大有症状肝血管瘤是一种安全的根治性手术。对于较小的病变或无症状患者,药物治疗是合理的。

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