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使用西罗莫司洗脱支架进行经皮冠状动脉介入治疗的血栓形成风险（来自注册研究和临床试验数据）。

Risk of thrombosis with the use of sirolimus-eluting stents for percutaneous coronary intervention (from registry and clinical trial data).

作者信息

Bavry Anthony A, Kumbhani Dharam J, Helton Thomas J, Bhatt Deepak L

机构信息

Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

出版信息

Am J Cardiol. 2005 Jun 15;95(12):1469-72. doi: 10.1016/j.amjcard.2005.02.015.

DOI:10.1016/j.amjcard.2005.02.015
PMID:15950574
Abstract

We conducted a meta-analysis on 6 studies in 2,963 patients who had coronary artery disease and received a sirolimus-eluting stent or a bare metal stent for revascularization. Compared with bare metal stents, sirolimus-eluting stents did not appear to increase the risk for thrombosis up to 13.5 months after coronary intervention (risk ratio 0.49, 95% confidence interval 0.22 to 1.12, p = 0.09).

摘要

我们对6项研究进行了荟萃分析，这些研究涉及2963例冠心病患者，他们接受了西罗莫司洗脱支架或裸金属支架进行血运重建。与裸金属支架相比，在冠状动脉介入治疗后长达13.5个月的时间里，西罗莫司洗脱支架似乎并未增加血栓形成风险（风险比0.49，95%置信区间0.22至1.12，p = 0.09）。

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