一种从巴西矛头蝮（巴西矛头蝮、金色矛头蝮）毒液中分离出的新型缓激肽增强肽（肽P）。
A new bradykinin-potentiating peptide (peptide P) isolated from the venom of Bothrops jararacussu (jararacuçu tapete, urutu dourado).
作者信息
Ferreira L A, Henriques O B, Lebrun I, Batista M B, Prezoto B C, Andreoni A S, Zelnik R, Habermehl G
机构信息
Serviço de Bioquímica-Lab, Cininas, Instituto Butantan, São Paulo, Brazil.
出版信息
Toxicon. 1992 Jan;30(1):33-40. doi: 10.1016/0041-0101(92)90499-u.
PMID:1595077
Abstract
Several bradykinin potentiators were identified in the venom of Bothrops jararacussu by chromatographic techniques and biological assays. One of them which was isolated inhibited the angiotensin-converting enzyme in vitro and potentiated the bradykinin-induced lowering of the arterial pressure in the rat.
摘要
通过色谱技术和生物测定法，在巴西矛头蝮蛇毒中鉴定出了几种缓激肽增强剂。其中一种被分离出来的物质在体外抑制血管紧张素转换酶，并增强缓激肽诱导的大鼠动脉血压降低作用。
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