Hernandez Katherine, Ramos Elizabeth, Seas Carlos, Henostroza German, Gotuzzo Eduardo
Instituto de Medicina Tropical "Alexander von Humboldt," Universidad Peruana Cayetano Heredia, Lima, Peru.
Infect Control Hosp Epidemiol. 2005 May;26(5):473-7. doi: 10.1086/502570.
To determine the incidence of and risk factors for surgical-site infections (SSIs) after abdominal surgery.
A cohort study was conducted from January to June 1998. CDC criteria for SSI and the NNIS System risk index were used.
A tertiary-care hospital in Peru.
Adult patients undergoing abdominal surgery who consented were enrolled and observed until 30 days after surgery. Patients who had undergone surgery at another hospital or who died or were transferred to another hospital within 24 hours after surgery were excluded.
Four hundred sixty-eight patients were enrolled. Their mean age was 37.2 years. One hundred twenty-five patients developed SSIs, 18% of which were identified after discharge. The overall incidence rate (IR) was 26.7%. The IR was 13.9% for clean, 15.9% for clean-contaminated, 13.5% for contaminated, and 47.2% for dirty interventions. The IR was 3.6% for NNIS System risk index 0 and 60% for index 3. Risk factors for SSI on logistic regression analysis were dirty or infected wound (RR, 3.8; CI95, 1.7-8.4), drain use longer than 9 days (RR, 6.0; CI95, 2.5-12.5), and length of surgery greater than the 75th percentile (RR, 2.1; CI95, 1.0-4.4). Patients with SSI had a longer hospital stay than did non-infected patients (14.0 vs 6.1 days; p < .001).
SSI is a major problem in this hospital, which has a higher IR (especially for clean interventions) than those of developed countries. In developing countries, prevention of SSI should include active surveillance and interventions targeting modifiable risk factors.
确定腹部手术后手术部位感染(SSI)的发生率及危险因素。
1998年1月至6月进行了一项队列研究。采用了疾病控制与预防中心(CDC)的SSI标准及国家医院感染监测系统(NNIS)风险指数。
秘鲁的一家三级护理医院。
同意参与的接受腹部手术的成年患者被纳入研究并观察至术后30天。排除在其他医院接受过手术或术后24小时内死亡或转至其他医院的患者。
共纳入468例患者。他们的平均年龄为37.2岁。125例患者发生了SSI,其中18%是在出院后发现的。总体发生率(IR)为26.7%。清洁手术的IR为13.9%,清洁-污染手术为15.9%,污染手术为13.5%,污秽-感染手术为47.2%。NNIS系统风险指数为0时IR为3.6%,指数为3时为60%。逻辑回归分析显示,SSI的危险因素包括伤口污秽或感染(相对危险度[RR]为3.8;95%置信区间[CI95]为1.7 - 8.4)、引流使用时间超过9天(RR为6.0;CI95为2.5 - 12.5)以及手术时间超过第75百分位数(RR为2.1;CI95为1.0 - 4.4)。发生SSI的患者住院时间比未感染患者更长(14.0天对6.1天;p < 0.001)。
SSI是这家医院的一个主要问题,其发生率(尤其是清洁手术)高于发达国家。在发展中国家,预防SSI应包括主动监测以及针对可改变危险因素的干预措施。