Glatter Kathryn A, Tuteja Dipika, Chiamvimonvat Nipavan, Hamdan Mohamed, Park Jeanny K
Department of Adult Cardiology, University of California-Davis, 4860 Y Street, Suite 2820, Sacramento, CA 95817, USA.
Pacing Clin Electrophysiol. 2005 Jun;28(6):591-3. doi: 10.1111/j.1540-8159.2005.50026.x.
Postural orthostatic tachycardia syndrome (POTS) is a rare disease characterized by syncope, sinus tachycardia, and orthostasis due to autonomic dysfunction.
Two women aged 26 and 24 years with severe POTS became pregnant. Both women experienced hyperemesis gravidarum with subsequent marked improvement in their POTS symptoms until 6 months gestation, when their syncope and sinus tachycardia caused clinical decompensation. Both patients delivered healthy babies at 37 weeks by elective cesarean section.
In long-term follow-up, both women reported improvement in their prepartum symptoms. We describe the first report, to our knowledge, of two successful pregnancy outcomes in severe POTS, including the first report of midodrine use in pregnant women.
体位性直立性心动过速综合征（POTS）是一种罕见疾病，其特征为晕厥、窦性心动过速以及因自主神经功能障碍导致的直立不耐受。
两名分别为26岁和24岁的重度POTS女性怀孕。两名女性均出现妊娠剧吐，随后其POTS症状显著改善，直至妊娠6个月时，晕厥和窦性心动过速导致临床失代偿。两名患者均在37周时通过择期剖宫产分娩出健康婴儿。
在长期随访中，两名女性均报告产前症状有所改善。据我们所知，我们描述了首例重度POTS患者成功妊娠结局的报告，包括首次报告在孕妇中使用米多君。
