Morgan Kate, Smith Angela, Blitshteyn Svetlana
School of Medicine and Public Health, Faculty of Health, The University of Newcastle, Newcastle, New South Wales, Australia.
HNE Health Libraries, Hunter New England Local Health District, Newcastle, New South Wales, Australia.
Int J Womens Health. 2022 Dec 24;14:1831-1847. doi: 10.2147/IJWH.S366667. eCollection 2022.
Postural Orthostatic Tachycardia Syndrome (POTS) is a disorder of the autonomic nervous system most commonly affecting women of reproductive age. Studies on POTS and pregnancy are limited, and there is a lack of clinical guidelines regarding assessment and management of pregnant women with POTS. The purpose of this review is to summarize data from the available studies on the topic of pregnancy in POTS and common comorbid conditions and to provide the clinical recommendations regarding evaluation and treatment of POTS in pregnant women, based on the available studies and clinical experience. We conclude that pregnancy appears to be safe for women with POTS and is best managed by a multi-disciplinary team with knowledge of POTS and its various comorbidities. Importantly, large, prospective studies are needed to better delineate the course and outcomes of pregnancy, as well as possible pregnancy-related complications in women with POTS. Clinicians should be aware of the clinical presentation, diagnostic criteria, and treatment options in pregnant women with POTS to optimize outcomes and improve medical care during pregnancy and post-partum period.
体位性直立性心动过速综合征（POTS）是一种自主神经系统疾病，最常影响育龄女性。关于POTS与妊娠的研究有限，且缺乏针对患有POTS的孕妇进行评估和管理的临床指南。本综述的目的是总结关于POTS患者妊娠及常见合并症这一主题的现有研究数据，并根据现有研究和临床经验，提供关于评估和治疗POTS孕妇的临床建议。我们得出结论，妊娠对患有POTS的女性似乎是安全的，最好由了解POTS及其各种合并症的多学科团队进行管理。重要的是，需要进行大型前瞻性研究，以更好地描绘妊娠的过程和结局，以及POTS女性可能出现的与妊娠相关的并发症。临床医生应了解POTS孕妇的临床表现、诊断标准和治疗选择，以优化结局并改善孕期和产后的医疗护理。
