溶组织内阿米巴和/或迪斯帕内阿米巴：墨西哥城HIV阳性/艾滋病患者的感染频率

Entamoeba histolytica and/or Entamoeba dispar: infection frequency in HIV+/AIDS patients in Mexico city.

作者信息

Moran Patricia, Ramos Fernando, Ramiro Manuel, Curiel Octavio, González Enrique, Valadez Alicia, Gómez Alejandro, García Gabriela, Melendro Emma I, Ximénez Cecilia

机构信息

Departamento de Medicina Experimental, Facultad de Medicina, UNAM, Mexico Distrito Federal, Mexico.

出版信息

Exp Parasitol. 2005 Jul;110(3):331-4. doi: 10.1016/j.exppara.2005.03.023.

DOI:10.1016/j.exppara.2005.03.023

PMID:15955334

Abstract

The objective of this work was to evaluate the frequency of Entamoeba histolytica/Entamoeba dispar intestinal infection in HIV+/AIDS subjects and their HIV- close relatives or sexual partners. Enteric parasites were investigated in stool samples by microscopic examination and E. histolytica and E. dispar were identified by PCR. We found by microscopic analysis in HIV+/AIDS group that the E. histolytica/E. dispar complex was present in 5.9% of the members, while in the HIV- group was 2.9%. With PCR we found that the E. histolytica prevalence was 25.3% in the HIV+/AIDS group and 18.5% in the HIV-group. The difference in the results obtained with the microscopic and PCR is due to the different sensibility of the procedures. Besides, we found patients who were infected with E. histolytica in both groups were asymptomatic cyst passers. Our results suggest that E. histolytica strains prevalent in the studied community appear to be of low pathogenic potential.

摘要

这项工作的目的是评估HIV阳性/AIDS患者及其HIV阴性的近亲或性伴侣中溶组织内阿米巴/迪斯帕内阿米巴肠道感染的频率。通过显微镜检查对粪便样本中的肠道寄生虫进行调查，并通过聚合酶链反应（PCR）鉴定溶组织内阿米巴和迪斯帕内阿米巴。我们通过显微镜分析发现在HIV阳性/AIDS组中，5.9%的成员存在溶组织内阿米巴/迪斯帕内阿米巴复合体，而在HIV阴性组中这一比例为2.9%。通过PCR我们发现，HIV阳性/AIDS组中溶组织内阿米巴的患病率为25.3%，HIV阴性组为18.5%。显微镜检查和PCR结果的差异是由于这两种检测方法的灵敏度不同。此外，我们发现两组中感染溶组织内阿米巴的患者均为无症状包囊携带者。我们的结果表明，在所研究社区中流行的溶组织内阿米巴菌株似乎致病潜力较低。