Micozzi M S, Brown E D, Edwards B K, Bieri J G, Taylor P R, Khachik F, Beecher G R, Smith J C
National Museum of Health and Medicine, Armed Forces Institute of Pathology, Washington, DC.
Am J Clin Nutr. 1992 Jun;55(6):1120-5. doi: 10.1093/ajcn/55.6.1120.
We determined serial changes in four major plasma carotenoid fractions (alpha-carotene, beta-carotene, lutein/zeaxanthin, and lycopene) in 30 men consuming defined daily doses of carotenoids from foods (broccoli, carrots, or tomato juice) or from purified beta-carotene in capsules (12 or 30 mg) for 6 wk while fed a controlled diet. Compared with baseline, beta-carotene increased in the 30- and 12-mg-capsule and carrot groups whereas alpha-carotene increased in the carrot group and lutein increased in the broccoli group. Lower lutein concentrations in recipients of beta-carotene capsules suggested an interaction between these two carotenoids. Lycopene declined in all groups except the tomato-juice group. Total carotenoid concentration changes only reflected the large increases in beta-carotene concentrations and not the smaller changes observed in other individual carotenoids. Overall, purified beta-carotene produced a greater plasma response than did similar quantities of carotenoids from foods sources. However, some foods increased plasma concentrations of certain carotenoids.
我们测定了30名男性在6周内连续服用规定日剂量的类胡萝卜素后的四种主要血浆类胡萝卜素组分（α-胡萝卜素、β-胡萝卜素、叶黄素/玉米黄质和番茄红素）的变化情况。这些男性食用的类胡萝卜素来自食物（西兰花、胡萝卜或番茄汁）或胶囊形式的纯化β-胡萝卜素（12毫克或30毫克），同时给予控制饮食。与基线相比，30毫克胶囊组、12毫克胶囊组和胡萝卜组的β-胡萝卜素增加，胡萝卜组的α-胡萝卜素增加，西兰花组的叶黄素增加。β-胡萝卜素胶囊服用者的叶黄素浓度较低，表明这两种类胡萝卜素之间存在相互作用。除番茄汁组外，其他所有组的番茄红素均下降。总类胡萝卜素浓度变化仅反映了β-胡萝卜素浓度的大幅增加，而未反映其他单个类胡萝卜素的较小变化。总体而言，纯化的β-胡萝卜素比来自食物来源的等量类胡萝卜素产生的血浆反应更大。然而，某些食物会增加特定类胡萝卜素的血浆浓度。
